睾丸切除术和雌二醇对大鼠脑区及腺垂体中乙酰胆碱酯酶活性的影响。
Effect of orchidectomy and estradiol on acetylcholinesterase activity in rat brain areas and adenohypophysis.
作者信息
Iramain C A, Egbunike G N, Owasoyo J O
出版信息
Experientia. 1979 Dec 15;35(12):1678-9. doi: 10.1007/BF01953268.
PMID:520502
Abstract
Orchidectomy plus estradiol administration decreased acetylcholinesterase activity in the rat cerebral cortex and mesencephalon, while in the amygdala it was increased. In the adenohypophysis, orchidectomy increased enzyme activity, but subsequent estradiol treatment decreased it. The hypothalamus did not respond to either manipulation.
摘要
睾丸切除术加雌二醇给药降低了大鼠大脑皮层和中脑的乙酰胆碱酯酶活性，而在杏仁核中该活性却升高了。在腺垂体中，睾丸切除术增加了酶活性，但随后的雌二醇治疗使其降低。下丘脑对这两种操作均无反应。
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