Swartz T A, Porath E B, Hornstein L
Dev Biol Stand. 1979;43:355-60.
A Rubella control programme was started in 1973 in Israel and aimed at: 1) the yearly immunization of all school girls aged 12; and (2) the rapid immunization of females 12 years old from the communal settlements. Both HEP77DE5 and Wistar RA 27/3 (WI-38) strains were used. A 5 year follow-up showed: (a) a vaccination coverage of 95%; (b) a seroconversion rate which approached 100% with persistent protective G. M.-antibody values; (c) about 15% of the females of childbearing age in the general population were devoid of Rubella HI antibody. During 1978 an extensive Rubella epidemic occurred in the general population 15-20% of whom were in the age group 15-44, whilst in the communal settlements no cases were observed in vaccinated people of the same age group.
以色列于1973年启动了风疹控制计划，目标是：1）对所有12岁在校女生进行年度免疫；2）对来自集体定居点的12岁女性进行快速免疫。使用了HEP77DE5和Wistar RA 27/3（WI-38）两种毒株。5年的随访结果显示：（a）疫苗接种覆盖率为95%；（b）血清转化率接近100%，且保护性GM抗体值持续存在；（c）普通人群中约15%的育龄女性缺乏风疹血凝抑制抗体。1978年，普通人群中发生了大规模风疹疫情，其中15% - 20%为15 - 44岁年龄组，而在集体定居点，同一年龄组的接种人群中未观察到病例。
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