Ah基因座：小鼠脑肿瘤形成遗传差异的生化基础。
The Ah locus: biochemical basis for genetic differences in brain tumor formation in mice.
作者信息
Levitt R C, Fysh J M, Jensen N M, Nebert D W
出版信息
Genetics. 1979 Aug;92(4):1205-10. doi: 10.1093/genetics/92.4.1205.
Abstract
Allelic differences at the Ah locus are showen to exist in the mouse brain. This finding probably explains inbred mouse strain differences in polycyclic hydrocarbon tumorigenesis of the brain described more than 35 years ago and may be important in understanding the etiology of genetic differences in certain human intracranial neoplasms.
摘要
已证明小鼠大脑中存在芳烃（Ah）位点的等位基因差异。这一发现或许可以解释35多年前描述的近交系小鼠大脑多环烃肿瘤发生的差异，并且对于理解某些人类颅内肿瘤遗传差异的病因可能具有重要意义。
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