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[人体非特异性生物抗性问题的群体遗传学研究方法。I. 问题阐述及研究方法基础。正常与患病新生儿及婴儿人体测量指标的分布参数]

[Population genetics approach to the problem of the nonspecific biological resistance of the human body. I. Statement of the problem and basis for the approach. Distribution parameters of anthropometric markers of normal and ill newborn infants and nurslings].

作者信息

Altukhov Iu P, Botvin'ev O K, Kurbatova O L

出版信息

Genetika. 1979;15(2):352-60.

PMID:520837
Abstract

Distributions of two metrical characters-the weight and the body length at birth are considered in several groups of healthy, diseased and dead newborns and infants. Significant differences in statistical parameters of these distributions (mean, standard deviation, skewness and kurtosis) are demonstrated for normal and malformated children. The increased number of children with minimal deviations from the mean values of characters (adaptive norm) is observed among healthy newborns, while in groups of diseased and dead children the frequency of individuals with extreme (especially low) values is increased. The principle of classification of individuals based simultaneously on two characteris is suggested and the problem of "average phenotype" classification by the number of characters is discussed.

摘要

在几组健康、患病和死亡的新生儿及婴儿中,研究了两个度量特征——出生时体重和身长的分布情况。结果表明,正常儿童和畸形儿童在这些分布的统计参数(均值、标准差、偏度和峰度)上存在显著差异。在健康新生儿中,观察到与特征均值(适应性规范)偏差最小的儿童数量增加,而在患病和死亡儿童组中,具有极端(尤其是低)值的个体频率增加。提出了同时基于两个特征对个体进行分类的原则,并讨论了根据特征数量进行“平均表型”分类的问题。

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