Zweymüller K
Fortschr Med. 1979 Dec 1;97(45):2107-11.
Construction principles, mechanical and animal experiments with various types of endoprostheses consisting of dense alumina are reported as well as the first results in man. A stable implantation of this biocompatible material is possible, if the primary attachment by means of special construction features and subtile operation technique is ensured. The definite dixation of the implant is provided by the ingrowth of newly formed bone tissue in circular running indentations. Therefore the use of bone cement, one of the critical points in replacement surgery, can be avoided. In tumor surgery the replacement of the proximal humerus by a ceramic prosthesis has proven to be successful. Equally satisfactory results could be achieved in the therapy of osteoarthritis of the hip with a metal-ceramic composite endoprosthesis.
本文报道了由致密氧化铝制成的各种类型内置假体的构建原理、力学及动物实验，以及首例人体实验结果。如果通过特殊的结构特征和精细的手术技术确保初次附着，这种生物相容性材料就能够实现稳定植入。新形成的骨组织向内生长进入环形凹槽，从而实现植入物的牢固固定。因此，可以避免使用骨水泥，而骨水泥是置换手术中的关键问题之一。在肿瘤手术中，使用陶瓷假体置换肱骨近端已被证明是成功的。使用金属 - 陶瓷复合内置假体治疗髋关节骨关节炎也能取得同样令人满意的结果。
