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膀胱和前列腺的肌肉肉瘤

Myosarcomas of the bladder and prostate.

作者信息

Mackenzie A R, Whitmore W F, Melamed M R

出版信息

Cancer. 1968 Oct;22(4):833-44. doi: 10.1002/1097-0142(196810)22:4<833::aid-cncr2820220422>3.0.co;2-i.

DOI:10.1002/1097-0142(196810)22:4<833::aid-cncr2820220422>3.0.co;2-i
PMID:5212307
Abstract

Of 32 patients seen in Memorial Center since 1920 with myosarcomas of the bladder or prostate 26 were male and six were female. The tumors arose in the bladder in 20, in the prostate in 11 and in one patient both organs were involved. Sarcomas of the bladder account for two or three of every thousand bladder cancers and for one of every thousand prostate cancers. Seventy-six patients, or approximately 10% of reported cases, have survived 3 years or more from diagnosis. Forty-five of those 76 sarcomas were reported as specific myosarcomas, i.e., embryonal rhabdomyosarcoma, adult rhabdomyosarcoma, leiomyosarcoma or combinations of those three. Thirty-six arose in the bladder, nine arose in the prostate. The most successful methods of treatment have been cystectomy for embryonal rhabdomyosarcoma of the bladder and segmental resection for leiomyosarcoma of the bladder. Rhabdomyosarcoma of the bladder and prostate has seldom been managed successfully, so that no particular treatment can be unconditionally recommended. Embryonal rhabdomyosarcoma of the prostate is as yet an incurable condition.

摘要

自1920年以来,在纪念中心就诊的32例膀胱或前列腺肌肉肉瘤患者中,26例为男性,6例为女性。肿瘤发生于膀胱20例,前列腺11例,1例两个器官均受累。膀胱肉瘤占每千例膀胱癌的两到三例,每千例前列腺癌的一例。76例患者,约占报告病例的10%,自诊断后存活3年或更长时间。这76例肉瘤中有45例报告为特定的肌肉肉瘤,即胚胎性横纹肌肉瘤、成人横纹肌肉瘤、平滑肌肉瘤或这三种的组合。36例发生于膀胱,9例发生于前列腺。最成功的治疗方法是膀胱胚胎性横纹肌肉瘤行膀胱切除术,膀胱平滑肌肉瘤行节段性切除术。膀胱和前列腺横纹肌肉瘤很少成功治疗,因此无法无条件推荐任何特定治疗方法。前列腺胚胎性横纹肌肉瘤目前仍是一种无法治愈的疾病。

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引用本文的文献

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Very rare synchronous malignant tumors of the Prostate: Leiomyosarcoma and adenocarcinoma - A case report and literature review.极为罕见的前列腺同步恶性肿瘤:平滑肌肉瘤和腺癌——病例报告及文献综述
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2
Leiomyosarcoma of the urinary bladder: A review and a report of two further cases.膀胱平滑肌肉瘤:文献综述及两例新病例报告
Arab J Urol. 2013 Jun;11(2):159-64. doi: 10.1016/j.aju.2013.03.004. Epub 2013 May 6.
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A case of high-grade leiomyosarcoma of the bladder with delayed onset and very poor prognosis.
一例高级别膀胱平滑肌肉瘤,起病隐匿,预后极差。
World J Surg Oncol. 2010 Mar 19;8:16. doi: 10.1186/1477-7819-8-16.
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Leiomyosarcoma of the urinary bladder presenting as life threatening gross hematuria.膀胱平滑肌肉瘤导致危及生命的大量血尿。
Med Oncol. 2010 Jun;27(2):562-7. doi: 10.1007/s12032-009-9248-2. Epub 2009 Jun 11.
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Urinary bladder leiomyosarcoma in adults.成人膀胱平滑肌肉瘤
Int Urol Nephrol. 2008;40(2):311-6. doi: 10.1007/s11255-007-9288-5.
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Leiomyosarcoma of the prostate. A case report.前列腺平滑肌肉瘤。病例报告。
Int Urol Nephrol. 1994;26(2):189-91. doi: 10.1007/BF02768285.
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The management of rhabdomyosarcoma in children and young adults.儿童和青年横纹肌肉瘤的管理
World J Surg. 1980 Jan;4(1):15-28. doi: 10.1007/BF02393087.
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Leukaemoid reaction in a case of leiomyosarcoma of the bladder.膀胱平滑肌肉瘤病例中的类白血病反应。
Postgrad Med J. 1977 Dec;53(626):766-8. doi: 10.1136/pgmj.53.626.766.