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两名明显健康的MkMk血型的日本人的红细胞既缺乏MN血型抗原,也缺乏具有Ss活性的唾液糖蛋白。

Two apparently healthy Japanese individuals of type MkMk have erythrocytes which lack both the blood group MN and Ss-active sialoglycoproteins.

作者信息

Tokunaga E, Sasakawa S, Tamaka K, Kawamata H, Giles C M, Ikin E W, Poole J, Anstee D J, Mawby W, Tanner M J

出版信息

J Immunogenet. 1979 Dec;6(6):383-90. doi: 10.1111/j.1744-313x.1979.tb00693.x.

Abstract

A Japanese blood donor (H. T.) and his brother (M. S.) are the first homozygous MkMk individuals described; their red cells lack, as expected, known antigens of the MNSs blood group system and also have no demonstrable MN-active and Ss-active glycoproteins. Both MkMk individuals have a naturally occurring atypical antibody in their serum. The antibody in the serum of H. T. is inhibited by MNSs-active glycoprotein preparations from normal erythrocytes.

摘要

一名日本献血者(H.T.)及其兄弟(M.S.)是首例被描述的纯合子MkMk个体;正如预期的那样,他们的红细胞缺乏MNSs血型系统的已知抗原,并且也没有可检测到的具有MN活性和Ss活性的糖蛋白。两名MkMk个体的血清中都有一种天然存在的非典型抗体。H.T.血清中的抗体被来自正常红细胞的具有MNSs活性的糖蛋白制剂所抑制。

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