Pollard M, Luckert P H
J Surg Oncol. 1979 Dec;12(4):371-7. doi: 10.1002/jso.2930120412.
Three transplantable rat prostate adenocarcinoma cell lines were assessed for patterns of metastasis, ie, routes of dissemination and larger organ(s) selected for implantation. Two lines (I and III) were disseminated only through ipsilateral lymphatic channels to the lungs. The third cell line (II) was disseminated through lymphatic and blood channels to lungs, liver, and kidneys. The pattern of spontaneous metastasis is a characteristic of the tumor cell; but there is evidence that the rate and extent of metastasis can be modified experimentally.
对三种可移植的大鼠前列腺腺癌细胞系的转移模式进行了评估，即扩散途径和选择植入的较大器官。两种细胞系（I和III）仅通过同侧淋巴通道扩散至肺部。第三种细胞系（II）通过淋巴和血液通道扩散至肺、肝和肾。自发转移模式是肿瘤细胞的一个特征；但有证据表明，转移的速率和程度可以通过实验进行改变。
