[链脲佐菌素诱导糖尿病大鼠后代肾脏的组织病理学变化]
[Histopathological changes in the kidneys of the progeny of rats with aloxan diabetes].
作者信息
Nasledova I D, Sokoloverova I M, Obegova R F
出版信息
Probl Endokrinol (Mosk). 1979 Nov-Dec;25(6):54-6.
PMID:523442
Abstract
A histological study (hematoxylin-eosin staining, and PAS-reaction) of the kidneys was carried out in 5 pubertal rats with diabetic test for glucose tolerance from the progeny of a female with alloxan diabetes and intact male. Changes of the type of diabetic intracapillary glomerulosclerosis were revealed. There were no changes in the kidneys of pubertal rats from the progeny of intact female and male, and an intact female and a male rat with alloxan diabetes.
摘要
对5只来自一只患有四氧嘧啶糖尿病的雌性大鼠与一只正常雄性大鼠后代的青春期大鼠进行了肾脏组织学研究（苏木精-伊红染色和PAS反应），这些大鼠进行了葡萄糖耐量糖尿病测试。发现了糖尿病性毛细血管内肾小球硬化类型的变化。来自正常雌性和雄性后代的青春期大鼠肾脏以及一只正常雌性和一只患有四氧嘧啶糖尿病的雄性大鼠的肾脏均未出现变化。
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