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[实验性动脉粥样硬化兔主动脉壁中γ球蛋白和纤维蛋白的定量荧光测定]

[Quantitative fluorometric determination of gamma globulin and fibrin in the aortic wall of rabbits with experimental atherosclerosis].

作者信息

Nagornev V A, Zubzhitskiĭ Iu N

出版信息

Arkh Patol. 1975;37(8):45-8.

PMID:52349
Abstract

By means of the fluometric method in 76 rabbits at definite stages of the development of experimental atherosclerosis in the aorta an increased amount of gamma-globulin and fibrin was established. An increase in the level of gamma-globulin was accompanied by fixation of beta1C-fraction of complement, which is characteristic of deposit of an immune complex. The most pronounced concentration of gamma-globulin was noted in areas of lysis and fragmentation of elastic fibres.

摘要

通过荧光测定法,在76只处于主动脉实验性动脉粥样硬化发展特定阶段的兔子身上,发现γ-球蛋白和纤维蛋白的含量增加。γ-球蛋白水平的升高伴随着补体β1C组分的固定,这是免疫复合物沉积的特征。在弹性纤维溶解和断裂区域,γ-球蛋白的浓度最为明显。

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