Lilleaasen P, Stokke O
Scand J Clin Lab Invest. 1979 Apr;39(2):125-32. doi: 10.1080/00365517909106084.
Two different programs of treatment, called moderate and extreme haemodilution, respectively, have been compared in patients undergoing aortic valve replacement. Serum electrolytes, urea, creatinine and osmolatity were satisfactory in both groups during and after surgery. A substantial retention of sodium took place in the moderately diluted patients. The extreme group lost more potassium in the urine than the moderate one. A small post-operative rise in creatinine indicates a slight kidney damage in the moderate group. Increased serum urea following moderate dilution might partly be due to increased protein catabolism.
在接受主动脉瓣置换术的患者中，对两种不同的治疗方案进行了比较，分别称为中度和极度血液稀释。手术期间及术后两组患者的血清电解质、尿素、肌酐和渗透压均令人满意。中度稀释的患者出现了大量的钠潴留。极度稀释组的尿钾流失比中度稀释组更多。中度稀释组术后肌酐略有升高，表明有轻微的肾损伤。中度稀释后血清尿素增加可能部分归因于蛋白质分解代谢增加。
