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[青蛙上皮细胞和神经元存活时间对某些物质浓度的依赖性]

[Dependence of frog epithelial cell and neuron survival time on the concentration of certain substances].

作者信息

Kiro M B, Suzdal'skaia I P, Geer L I, Ivanova A I

出版信息

Tsitologiia. 1979 Nov;21(11):1296-304.

PMID:524458
Abstract

The frog cornea epitelial cells, nervous cells of spinal ganglia and of urinary bladder have been found to survive in vitro, in the presence of subtoxical concentrations of chloral hydrate, urea, ethanol or methanol added to the Ringer solution, longer than control preparations. The above drugs added both in lower and higher concentrations lead to cell damages, thus reducing the cell survival time, which was tested by the capacity to deposit granules of a vital dye - neutral red.

摘要

已发现青蛙角膜上皮细胞、脊髓神经节神经细胞和膀胱神经细胞,在添加到任氏液中的水合氯醛、尿素、乙醇或甲醇处于亚毒性浓度时,能在体外比对照制剂存活更长时间。上述药物无论添加低浓度还是高浓度都会导致细胞损伤,从而缩短细胞存活时间,这是通过细胞摄取活体染料中性红颗粒的能力来检测的。

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1
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Tsitologiia. 1979 Nov;21(11):1296-304.
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