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Conformational differences in neurohypophyseal peptides: a countercurrent distribution and partition chromatography study.

作者信息

Gordon W, Havran R T, Schwartz I L, Walter R

出版信息

Proc Natl Acad Sci U S A. 1968 Aug;60(4):1353-5. doi: 10.1073/pnas.60.4.1353.

DOI:10.1073/pnas.60.4.1353
PMID:5244744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC224925/
Abstract
摘要

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Conformational differences in neurohypophyseal peptides: a countercurrent distribution and partition chromatography study.神经垂体肽的构象差异:逆流分布和分配色谱研究
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Simultaneous synthesis of 1-hemi-D-cystine-oxytocin and oxytocin and separation of the diastereoisomers by partition chromatography on sephadex and by countercurrent distribution.1-半胱氨酸-催产素和催产素的同时合成以及通过葡聚糖凝胶上的分配色谱法和逆流分配法分离非对映异构体。
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(1-(1-2-Hydroxy-3-mercaptopropanoic acid))-oxytocin, a highly potent analogue of oytocin not bound by neurophysin.(1-(1-2-羟基-3-巯基丙酸))-催产素,一种不受神经垂体素结合的高效催产素类似物。
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引用本文的文献

1
Oxytocin and neurohypophyseal peptides: spectral assignment and conformational analysis by 220 MHz nuclear magnetic resonance.催产素与神经垂体肽:通过220兆赫核磁共振进行光谱归属及构象分析
Proc Natl Acad Sci U S A. 1969 Dec;64(4):1269-75. doi: 10.1073/pnas.64.4.1269.
2
Conformational studies of oxytocin, lysine vasopressin, arginine vasopressin, and arginine vasotocin by carbon-13 nuclear magnetic resonance spectroscopy.通过碳-13核磁共振光谱法对催产素、赖氨酸加压素、精氨酸加压素和精氨酸催产素进行的构象研究。
Proc Natl Acad Sci U S A. 1973 Jul;70(7):2086-90. doi: 10.1073/pnas.70.7.2086.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
A highly potent analogue of oxytocin, desamino-oxytocin.一种高效的催产素类似物,去氨基催产素。
J Biol Chem. 1962 May;237:1563-6.
3
CRYSTALLINE DEAMINO-OXYTOCIN.
Science. 1964 Feb 7;143(3606):545-8. doi: 10.1126/science.143.3606.545.
4
Syntheses and pharmacological properties of selenium isologs of oxytocin and deamino-oxytocin.
J Am Chem Soc. 1967 Jul 19;89(15):3892-8. doi: 10.1021/ja00991a037.
5
A study of isologous 1,2-dithiolane, 1,2-diselenolanoe, and 1-thia-2-selenolane derivatives.
J Am Chem Soc. 1966 Apr 20;88(8):1759-62. doi: 10.1021/ja00960a032.
6
Simultaneous synthesis of 1-hemi-D-cystine-oxytocin and oxytocin and separation of the diastereoisomers by partition chromatography on sephadex and by countercurrent distribution.1-半胱氨酸-催产素和催产素的同时合成以及通过葡聚糖凝胶上的分配色谱法和逆流分配法分离非对映异构体。
J Am Chem Soc. 1966 Mar 20;88(6):1310-3. doi: 10.1021/ja00958a040.
7
Deamino-oxytocin. Its isolation by partition chromatography on Sephadex and crystallization from water, and its biological activities.去氨基催产素。通过在葡聚糖凝胶上的分配色谱法进行分离以及从水中结晶得到的去氨基催产素及其生物活性。
J Biol Chem. 1965 Nov;240(11):4264-6.
8
6-Hemi-L-selenocystine-oxytocin and 1-deamino-6-hemi-L-selenocystine-oxytocin, highly potent isologs of oxytocin and 1-deamino-oxytocin.
J Am Chem Soc. 1965 Sep 20;87(18):4192-3. doi: 10.1021/ja01096a036.