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On the location and structure of the active sites of antibody molecules.

作者信息

Singer S J, Thorpe N O

出版信息

Proc Natl Acad Sci U S A. 1968 Aug;60(4):1371-8. doi: 10.1073/pnas.60.4.1371.

DOI:10.1073/pnas.60.4.1371
PMID:5244745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC224928/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4f/224928/94de28af9736/pnas00122-0324-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4f/224928/94de28af9736/pnas00122-0324-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b4f/224928/94de28af9736/pnas00122-0324-a.jpg

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1
On the location and structure of the active sites of antibody molecules.关于抗体分子活性位点的位置和结构
Proc Natl Acad Sci U S A. 1968 Aug;60(4):1371-8. doi: 10.1073/pnas.60.4.1371.
2
The affinity-labeled residues in antibody active sites. II. Nearest-neighbor analyses.抗体活性位点中的亲和标记残基。II. 邻位分析。
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3
Localization within the heavy chain sequence of tyrosyl peptides from the combining sites in a rabbit anti-3-azopyridine antibody preparation.兔抗3-偶氮吡啶抗体制剂中结合位点酪氨酸肽重链序列内的定位
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Affinity labeling by m-nitrobenzenediazonium fluoroborate of porcine anti-dinitrophenyl antibodies. Localization of labeled tyrosine in the -chains.用氟硼酸间硝基苯重氮盐对猪抗二硝基苯基抗体进行亲和标记。标记酪氨酸在重链中的定位。
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Isr J Med Sci. 1969 May-Jun;5(3):338-51.

引用本文的文献

1
Evolutionary pattern of specificity regions in light chains of immunoglobulins.免疫球蛋白轻链特异性区域的进化模式。
Biochem Genet. 1969 Apr;3(2):109-17. doi: 10.1007/BF00520347.
2
Site-directed cross-linking: a new approach to mapping antibody combining sites.定点交联：绘制抗体结合位点的一种新方法。
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1421-4. doi: 10.1073/pnas.68.7.1421.
3
The covalent structure of an entire gammaG immunoglobulin molecule.完整的γG免疫球蛋白分子的共价结构。

本文引用的文献

1
AFFINITY LABELING OF THE ACTIVE SITES OF ANTIBODIES TO THE 2,4-DINITROPHENYL HAPTEN.针对2,4 - 二硝基苯基半抗原的抗体活性位点的亲和标记
Biochemistry. 1963 Sep-Oct;2:979-88. doi: 10.1021/bi00905a014.
2
Affinity labeling-a general method for labeling the active sites of antibody and enzyme molecules.亲和标记——一种标记抗体和酶分子活性位点的通用方法。
Biochemistry. 1962 Nov;1:1031-9. doi: 10.1021/bi00912a013.
3
Reduction of gamma-globulins.γ球蛋白减少
Proc Natl Acad Sci U S A. 1969 May;63(1):78-85. doi: 10.1073/pnas.63.1.78.
4
[Molecular basis of antibody formation].[抗体形成的分子基础]
Naturwissenschaften. 1969 Apr;56(4):195-205. doi: 10.1007/BF01166814.
5
Six BALB-c IgA myeloma proteins that bind beta-(1-6)-D-galactan. Partial amino acid sequences and idiotypes.六种结合β-(1-6)-D-半乳聚糖的BALB-c IgA骨髓瘤蛋白。部分氨基酸序列和独特型。
J Exp Med. 1973 Nov 1;138(5):1095-105. doi: 10.1084/jem.138.5.1095.
6
Conformational significance of the intrachain disulfide linkages in immunoglobulins.免疫球蛋白中链内二硫键的构象意义
Proc Natl Acad Sci U S A. 1970 Nov;67(3):1085-92. doi: 10.1073/pnas.67.3.1085.
Arch Biochem Biophys. 1962 Sep;Suppl 1:174-80.
4
On structural and functional relations between antibodies and proteins of the gamma-system.关于抗体与γ-系统蛋白质之间的结构和功能关系
Proc Natl Acad Sci U S A. 1962 Jun 15;48(6):1035-42. doi: 10.1073/pnas.48.6.1035.
5
The preparation and some properties of purified antibody specific for the 2,4-dinitrophenyl group.针对2,4-二硝基苯基基团的纯化抗体的制备及其某些性质
J Exp Med. 1960 Dec 1;112(6):1195-210. doi: 10.1084/jem.112.6.1195.
6
Structure and function of haemoglobin. 3. A three-dimensional fourier synthesis of human deoxyhaemoglobin at 5.5 Angstrom resolution.血红蛋白的结构与功能。3. 5.5埃分辨率下人类脱氧血红蛋白的三维傅里叶合成。
J Mol Biol. 1967 Aug 28;28(1):117-56. doi: 10.1016/s0022-2836(67)80082-2.
7
Affinity labeling of the active sites of rabbit anti-2,4-dinitrophenyl antibodies with m-nitrobenzenediazonium fluoroborate.用间硝基苯重氮氟硼酸盐对兔抗2,4-二硝基苯基抗体的活性位点进行亲和标记。
Biochemistry. 1967 Mar;6(3):873-81. doi: 10.1021/bi00855a031.
8
Accelerated automatic chromatographic analysis of peptides on a spherical resin.球形树脂上肽的加速自动色谱分析
Anal Biochem. 1966 Jul;16(1):91-106. doi: 10.1016/0003-2697(66)90084-4.
9
Variations in amino-acid sequence near the disulphide bridges of Bence-Jones proteins.本-周蛋白二硫键附近氨基酸序列的变异
Nature. 1966 Jan 22;209(5021):370-3. doi: 10.1038/209370a0.
10
Affinity labeling of antibodies to the p-azophenyltrimethylammonium hapten and a structural relationship among antibody active sites of different specificities.对-偶氮苯基三甲基铵半抗原抗体的亲和标记及不同特异性抗体活性位点之间的结构关系
Biochem Biophys Res Commun. 1965 Jul 26;20(3):315-20. doi: 10.1016/0006-291x(65)90366-9.