Antal M, Gaál O, Gergely A, Nagy K, Szépvölgyi J
Z Ernahrungswiss. 1979 Sep;18(3):184-90. doi: 10.1007/BF02020599.
Dams of a Wistar-derived OETI strain were offered a 15% aqueous ethanol solution as drinking-fluid immediately after delivery until weanling. Their offsprings also received the same drinking-fluid from weanling (Group A). Another group of rats received the 15% aqueous ethanol solution only after weanling (Group B). In response to ethanol treatment the retardation of growth was the most marked in Group A, but the growth of rats in Group B was also decreased significantly as compared to that of controls. Hepatic glycogen content was diminished in all of the ethanol-treated groups. Triglyceride content was increased in the livers of female rats in Group A. By comparing earlier results with the present findings the authors point to the importance of strain and sex in experiments when parameters for hepatic metabolism are studied in response to ethanol.
给源自Wistar的OETI品系的母鼠在分娩后立即提供15%的乙醇水溶液作为饮剂，直至断奶。它们的后代从断奶起也饮用相同的饮剂（A组）。另一组大鼠仅在断奶后饮用15%的乙醇水溶液（B组）。作为对乙醇处理的反应，A组生长迟缓最为明显，但与对照组相比，B组大鼠的生长也显著下降。所有乙醇处理组的肝糖原含量均减少。A组雌性大鼠肝脏中的甘油三酯含量增加。通过将早期结果与目前的发现进行比较，作者指出在研究肝脏代谢参数对乙醇的反应时，品系和性别在实验中的重要性。
