Tengrup I, Zederfeldt B
Acta Chir Scand. 1979;145(5):293-5.
Nine female patients were given zinc sulphate (Solvezinc) 220 mg three times daily for 4 weeks prior to cholecystectomy. Mean serum zinc before zinc treatment was 17 +/- 0.8 mumol/l and rose 25 +/- 1.6 mumol/l after zinc treatment. 6 hours postoperatively serum zinc was 13 +/- 1.4 mumol/l. Thereafter it gradually increased to 20 +/- 0.7 mumol/l by the third postoperative day. The present investigation thus shows that pretreatment with zinc increases the serum zinc level but does not prevent the drop in serum zinc in connection with cholecystectomy. However, with the pretreatment serum zinc never falls below the normal range.
9名女性患者在胆囊切除术前4周每天3次服用220毫克硫酸锌(Solvezinc)。锌治疗前血清锌平均值为17±0.8微摩尔/升,锌治疗后升至25±1.6微摩尔/升。术后6小时血清锌为13±1.4微摩尔/升。此后,到术后第三天逐渐升至20±0.7微摩尔/升。本研究表明,锌预处理可提高血清锌水平,但不能防止胆囊切除术后血清锌水平下降。然而,经过预处理血清锌从未降至正常范围以下。