Parkes J D, Schachter M
Acta Neurol Scand. 1979 Oct;60(4):250-4. doi: 10.1111/j.1600-0404.1979.tb02976.x.
Thirty-four subjects with the narcoleptic syndrome were treated with mazindol 3--8 mg daily for 1 year. Treatment cuased a sustained improvement in narcolepsy, but had no effect on cataplexy or sleep paralysis. The response to mazindol was excellent in six subjects, good in 14, moderate in 12 and poor in two. No cardiovascular effects, haematological toxicity, tolerance or dependence occurred. Mazindol 6 mg had the same effect on narcolepsy as d-amphetamine 50 mg, but caused less side effects.
34名发作性睡病综合征患者每日服用3 - 8毫克马吲哚，持续治疗1年。治疗使发作性睡病症状持续改善，但对猝倒症或睡眠瘫痪无效。6名患者对马吲哚反应极佳，14名良好，12名中等，2名较差。未出现心血管效应、血液学毒性、耐受性或依赖性。6毫克马吲哚对发作性睡病的疗效与50毫克右旋苯丙胺相同，但副作用较少。
