Rolschau J, Date J, Kristoffersen K
Acta Obstet Gynecol Scand. 1979;58(4):343-6. doi: 10.3109/00016347909154593.
The effect of a folic acid supplment on birth weight and placental weight in women delivering in the early summer in Denmark was investigated. Thirty-six women with normal pregnancy and expected delivery in the first half of June were selected consecutively. They were paired two and two, and allotted to two groups, one of which was supplied daily with 5 mg folic acid, and the second with tablets without folic acid, from the 23rd week of pregnancy. A significant correlation was found between erythrocyte folic acid and birth weight. The infants in the folic acid group were 12.7 per cent heavier than those in the control group (p less than 0.01). A similar difference was found with regard to placental weight and the number of placental cells.
研究了叶酸补充剂对丹麦初夏分娩女性的出生体重和胎盘重量的影响。连续选取了36名妊娠正常且预计在6月上半月分娩的女性。将她们两两配对，分为两组，其中一组从妊娠第23周起每天补充5毫克叶酸，另一组服用不含叶酸的片剂。发现红细胞叶酸与出生体重之间存在显著相关性。叶酸组的婴儿比对照组重12.7%（p<0.01）。在胎盘重量和胎盘细胞数量方面也发现了类似差异。
