离液剂对颗粒状蛋白质和非电解质的增溶作用。
Solubilization of particulate proteins and nonelectrolytes by chaotropic agents.
作者信息
Hatefi Y, Hanstein W G
出版信息
Proc Natl Acad Sci U S A. 1969 Apr;62(4):1129-36. doi: 10.1073/pnas.62.4.1129.
Abstract
Chaotropic ions (those ions which favor the transfer of apolar groups to water) provide a highly effective means for the resolution of membranes and multicomponent enzymes and for increasing the water solubility of particular proteins and nonelectrolytes. The action of chaotropic agents is related to their effect on the structure and lipophilicity of water.
摘要
离液序列高的离子（即那些有利于将非极性基团转移至水中的离子）为细胞膜、多组分酶的分离以及增加特定蛋白质和非电解质的水溶性提供了一种非常有效的方法。离液剂的作用与其对水的结构和亲脂性的影响有关。
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