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[Synthesis and analysis of possible nitrazepam-metabolites. 4. Chemistry and analysis of benzodiazepin-derivatives].

作者信息

Beyer K H, Sadée W

出版信息

Arch Pharm Ber Dtsch Pharm Ges. 1969 Feb;302(2):152-7. doi: 10.1002/ardp.19693020211.

DOI:10.1002/ardp.19693020211
PMID:5260845
Abstract
摘要

相似文献

1
[Synthesis and analysis of possible nitrazepam-metabolites. 4. Chemistry and analysis of benzodiazepin-derivatives].
Arch Pharm Ber Dtsch Pharm Ges. 1969 Feb;302(2):152-7. doi: 10.1002/ardp.19693020211.
2
Quinazolines and 1,4-benzodiazepines. XL. The synthesis of metabolites of 7-chloro-1-(2-diethylaminoethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one.喹唑啉类和1,4-苯并二氮杂䓬类。XL。7-氯-1-(2-二乙氨基乙基)-5-(2-氟苯基)-1,3-二氢-2H-1,4-苯并二氮杂䓬-2-酮代谢物的合成。
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3
Synthesis and central nervous system effects of 8.9-dihydro(1)benzazepino(3,2.1-ak)(1,4)benzodiazepin-1(2H)-ones and (1) binzazepino(3,2,1-jk)(1,4)benzodiazepin-1(2H)-ones.8,9-二氢(1)苯并氮杂卓并(3,2.1-ak)(1,4)苯并二氮杂卓-1(2H)-酮和(1)苯并氮杂卓并(3,2,1-jk)(1,4)苯并二氮杂卓-1(2H)-酮的合成及对中枢神经系统的作用
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Determination of nitrazepam in blood and urine by gas liquid chromatography.
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Stereoselective synthesis of methyl (Z)-(4,4-difluoro-2,3,4,5-tetrahydro-1H-1-benzazepin-5-ylidene)acetate using a dianion Horner-Wadsworth-Emmons reagent.使用双负离子霍纳尔－沃兹沃思－埃蒙斯试剂立体选择性合成(Z)-(4,4-二氟-2,3,4,5-四氢-1H-1-苯并氮杂卓-5-亚基)乙酸甲酯
Chem Pharm Bull (Tokyo). 2005 May;53(5):589-90. doi: 10.1248/cpb.53.589.
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3-substituted 1,4-benzodiazepin-2-ones.3-取代的1,4-苯并二氮杂卓-2-酮
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[Derivatives of benzo-(f)-diazepine-1,4 used in therapeutics. I. Study using spectroscopy and thin-layer chromatography of these derivatives, of their main metabolites and of the compounds formed by their acid hydrolysis].[用于治疗的苯并-(f)-二氮杂卓-1,4衍生物。I. 对这些衍生物、其主要代谢产物以及由其酸水解形成的化合物进行光谱学和薄层色谱研究]
Ann Pharm Fr. 1970 May;28(5):343-54.
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[Rapid thin-layer chromatography demonstration of tranquilizers of the benzodiazepin series and thymoleptic drugs].[苯二氮䓬类镇静剂和抗抑郁药物的快速薄层色谱演示]
Med Welt. 1969 Feb 15;7:369-72.

引用本文的文献

1
Detection and identification of nitrazepam and related compounds by thin-layer chromatography.
Arch Toxikol. 1970;27(1):71-8. doi: 10.1007/BF00312375.
2
On the urinary excretion of nitrazepam and its metabolites.
Arch Toxikol. 1971;28(3):214-21. doi: 10.1007/BF00330251.
3
[Analytical data of flunitrazepam (rohypnol), a new benzodiazepine-derivative, in special consideration of its metabolites (author's transl)].
Z Rechtsmed. 1978 May 29;81(2):107-17. doi: 10.1007/BF00203870.