通过比较烟草花叶病毒RNA在不同植物中合成的外壳蛋白来证明遗传密码在体内的通用性。
Demonstration of the universality of the genetic code in vivo by comparison of the coat proteins synthesized in different plants by tobacco mosaic virus RNA.
作者信息
Okada Y, Nozu Y, Ohno T
出版信息
Proc Natl Acad Sci U S A. 1969 Aug;63(4):1189-95. doi: 10.1073/pnas.63.4.1189.
Abstract
The amino acid sequence of the coat protein of tobacco mosaic virus (TMV) synthesized in the garden zinnia (Compositae family) is compared with that synthesized in tobacco (Solanaceae family) by using the same preparation of TMV-RNA as messenger. The Compositae family is the most advanced group, and the Solanaceae family is a relatively advanced group in the plant kingdom. Both amino acid sequences are identical, including acetylserine as the N-terminal amino acid. This gives direct evidence that the RNA codon in vivo in the plant kingdom is universal between Compositae and Solanaceae families.
摘要
通过使用相同的烟草花叶病毒（TMV）-RNA制剂作为信使，比较了在百日草（菊科）中合成的烟草花叶病毒外壳蛋白的氨基酸序列与在烟草（茄科）中合成的氨基酸序列。菊科是植物界中最进化的类群，茄科是相对进化的类群。两种氨基酸序列是相同的，包括N端氨基酸乙酰丝氨酸。这直接证明了在植物界中，菊科和茄科体内的RNA密码子是通用的。
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