关于噬菌体T4不完全染色体的复制
On the replication of incomplete chromosomes of phage T4.
作者信息
Mosig G, Werner R
出版信息
Proc Natl Acad Sci U S A. 1969 Oct;64(2):747-54. doi: 10.1073/pnas.64.2.747.
Abstract
Some small particles of phage T4 contain incomplete chromosomes measuring two thirds of the length of normal T4 chromosomes. They cannot produce progeny phage after single infection because their incomplete chromosomes lack random segments of the genetic map. We have investigated the replication of DNA following single infection with small particles. Our results indicate that approximately two thirds of the incomplete chromosomes can initiate DNA replication and apparently extend the process from a genetically fixed origin to one end of the molecule. However, few if any of the incomplete chromosomes can initiate a second round of replication. The incomplete chromosomes which do not replicate also do not attach to bacterial membranes.
摘要
一些T4噬菌体的小颗粒含有不完整的染色体，其长度为正常T4染色体的三分之二。单次感染后它们无法产生子代噬菌体，因为其不完整的染色体缺少遗传图谱中的随机片段。我们研究了用小颗粒单次感染后的DNA复制情况。我们的结果表明，大约三分之二的不完整染色体能够起始DNA复制，并且显然能将该过程从一个基因固定的起点延伸至分子的一端。然而，几乎没有不完整染色体能够起始第二轮复制。未进行复制的不完整染色体也不会附着于细菌膜上。
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2
Sedimentation rate as a measure of molecular weight of DNA.沉降速率作为DNA分子量的一种衡量指标。
Biophys J. 1963 Jul;3(4):309-21. doi: 10.1016/s0006-3495(63)86823-x.
3
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