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抗生素灌洗治疗慢性骨髓炎。

Antibiotic irrigation-perfusion treatment for chronic osteomyelitis.

作者信息

Boda A

出版信息

Arch Orthop Trauma Surg (1978). 1979 Oct;95(1-2):31-5. doi: 10.1007/BF00379167.

DOI:10.1007/BF00379167
PMID:526124
Abstract

This paper reports 125 antibiotic irrigation-perfusion treatments of chronic osteomyelitic patients. The localisation of the osteomyelitic process, the duration of the disease, the duration of the treatment, the age distributions of the patients, and the results of the treatment are noted. The study revealed that only one third of the patients healed after the irrigation-perfusion treatment. This rate falls short of the results reported in the literature. The possible causes are discussed and emphasis is given to the technical problems. On the basis of this survey the author is of the opinion that this method is to be employed only in exceptional cases of bone infections. The indication and contraindications are precisely defined.

摘要

本文报道了对慢性骨髓炎患者进行的125次抗生素冲洗-灌注治疗。记录了骨髓炎病变的部位、病程、治疗时长、患者的年龄分布以及治疗结果。研究显示,冲洗-灌注治疗后仅有三分之一的患者痊愈。该治愈率低于文献报道的结果。文中讨论了可能的原因,并着重强调了技术问题。基于此项调查,作者认为该方法仅适用于骨感染的特殊病例。明确界定了适应证和禁忌证。

相似文献

1
Antibiotic irrigation-perfusion treatment for chronic osteomyelitis.抗生素灌洗治疗慢性骨髓炎。
Arch Orthop Trauma Surg (1978). 1979 Oct;95(1-2):31-5. doi: 10.1007/BF00379167.
2
[Antibiotic perfusion therapy in osteomyelitis].[骨髓炎的抗生素灌注治疗]
Magy Traumatol Orthop Helyreallito Seb. 1974 Jan;17(1):11-8.
3
[Bacteriology of chronic osteomyelitic focus].
Chir Narzadow Ruchu Ortop Pol. 1982;47(5-6):383-7.
4
Management of chronic osteomyelitis using an irrigation suction technique.采用冲洗吸引技术治疗慢性骨髓炎。
Int Orthop. 1988;12(4):265-8. doi: 10.1007/BF00317821.
5
Organism isolation and serum bactericidal titers in oral antibiotic therapy for pediatric osteomyelitis.
South Med J. 1996 Jan;89(1):68-70. doi: 10.1097/00007611-199601000-00012.
6
Irrigation-suction technic in the treatment of acute hematogenous osteomyelitis, chronic osteomyelitis, and acute and chronic joint infections.
South Med J. 1970 Jul;63(7):745-54. doi: 10.1097/00007611-197007000-00001.
7
Cortical bone fenestrations with continuous antibiotic irrigation to mediate hematogenous tibial osteomyelitis in children.采用连续抗生素冲洗的皮质骨开窗术治疗儿童血源性胫骨骨髓炎。
J Pediatr Orthop B. 2010 Nov;19(6):497-506. doi: 10.1097/BPB.0b013e32833cb8a2.
8
Treatment of chronic osteomyelitis with the continuous irrigation-suction method.持续冲洗吸引法治疗慢性骨髓炎
Acta Orthop Scand. 1972;43(1):25-31. doi: 10.3109/17453677208988660.
9
The bacteriological diagnosis and antibiotic treatment of haematogenous vertebral osteomyelitis in adults.成人血源性椎体骨髓炎的细菌学诊断与抗生素治疗
Aust N Z J Surg. 1978 Feb;48(1):81-3. doi: 10.1111/j.1445-2197.1978.tb05812.x.
10
[Antibiotic therapy of osteomyelitis (literature survey)].
Khirurgiia (Mosk). 1975 Apr(4):141-6.

引用本文的文献

1
Chronic osteomyelitis.慢性骨髓炎。
Curr Infect Dis Rep. 2012 Oct;14(5):566-75. doi: 10.1007/s11908-012-0286-0.

本文引用的文献

1
Biochemistry of inflammation.炎症的生物化学
Lancet. 1947 May 17;1(6455):660-2. doi: 10.1016/s0140-6736(47)91407-4.
2
THE VALUE OF DAKIN'S SOLUTION IN THE TREATMENT OF ACUTE AND CHRONIC OSTEOMYELITIS.达金氏溶液在急慢性骨髓炎治疗中的价值
Ann Surg. 1922 Jun;75(6):708-16. doi: 10.1097/00000658-192206000-00011.
3
INTRAMEDULLARY PRESSURE WITH PARTICULAR REFERENCE TO MASSIVE DIAPHYSEAL BONE NECROSIS: EXPERIMENTAL OBSERVATIONS.髓内压,特别涉及大量骨干骨坏死:实验观察
Ann Surg. 1938 Jul;108(1):127-40. doi: 10.1097/00000658-193807000-00009.
4
Importance of soft tissue to treatment of chronic osteomyelitis.软组织对慢性骨髓炎治疗的重要性。
JAMA. 1962 Apr 21;180:198-203. doi: 10.1001/jama.1962.03050160014004.
5
[IS THERE A TRUE ANTIBACTERIAL EFFECT WHEN CHLORAMPHENICOL SUCCINATE IS USED LOCALLY? STUDIES ON THE SPLITTING OF CHLORAMPHENICOL SUCCINATE IN HUMAN BODY FLUIDS AND TISSUES].[琥珀氯霉素局部使用时是否存在真正的抗菌作用?人体体液和组织中琥珀氯霉素的分解研究]
Dtsch Med Wochenschr. 1965 Jan 29;90:204-7. doi: 10.1055/s-0028-1111318.
6
Treatment of osteomyelitis and infected wounds by closed irrigation with a detergent-antibiotic solution.用去污剂 - 抗生素溶液进行封闭冲洗治疗骨髓炎和感染伤口。
Acta Orthop Scand. 1962;32:324-33. doi: 10.3109/17453676208989589.
7
[The antibacterial irrigation drainage of surgical infections].[手术感染的抗菌冲洗引流]
Dtsch Med Wochenschr. 1962 Jul 27;87:1485-92. doi: 10.1055/s-0028-1112092.
8
Acute haematogenous osteomyelitis: its pathology and treatment.急性血源性骨髓炎:其病理学与治疗
Bull Hosp Joint Dis. 1953 Apr;14(1):5-23.
9
[Clinical aspects and therapy of wound infection following nailing of the femoral neck].[股骨颈骨折内固定术后伤口感染的临床情况与治疗]
Chirurg. 1966 Sep;37(9):400-4.
10
Closed irrigation-suction of spine infections. A review of four successfully treated cases of pyogenic vertebral osteomyelitis.脊柱感染的闭式冲洗吸引术。4例化脓性椎体骨髓炎成功治疗病例的回顾。
JAMA. 1966 May 30;196(9):761-4.