Taiushev K G, Olenev S N, Tsvetkova I P, Orlov V A
Arkh Anat Gistol Embriol. 1979 Dec;77(12):18-25.
By means of cytophotometry and a computer in the cardiac intramural neural plexus of 17 experimental and 17 control rabbits acetilcholine esterase (AChE) activity (revealed by Karnovsky--Roots' method) was investigated. It was stated that a prolonged electrostimulation of the area hypothalamica posterior (AHP) produced statistically significant 2-fold decrease of AChE activity in the cardiac neural cells and fibres. When the stimulation of AHP was stopped, the decreased enzymatic activity was observed for the first two weeks, then by the end of the 4th week it again reached its control level. The results of the work were discussed in view of possible disorders of regulating vegetative-trophic effects of the posterior hypothalamus on innervative and executive tissue elements of the heart.
通过细胞光度测定法并借助计算机,对17只实验兔和17只对照兔心脏壁内神经丛中的乙酰胆碱酯酶(AChE)活性(采用卡诺夫斯基 - 鲁茨法显示)进行了研究。结果表明,对下丘脑后部区域(AHP)进行长时间电刺激会使心脏神经细胞和纤维中的AChE活性在统计学上显著降低两倍。当停止对AHP的刺激时,在前两周观察到酶活性下降,然后在第4周结束时它再次达到对照水平。鉴于下丘脑后部对心脏的神经支配和执行组织成分的营养调节作用可能出现紊乱,对该研究结果进行了讨论。