脑啡肽的四肽酰胺类似物：C末端在决定阿片样物质活性特征中的作用 - Suppr

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超能文献

Tetrapeptide-amide analogues of enkephalin: the role of C-terminus in determining the character of opioid activity.

作者信息

Rónai A Z, Székely J I, Berzétei I, Miglécz E, Bajusz S

出版信息

Biochem Biophys Res Commun. 1979 Dec 28;91(4):1239-49. doi: 10.1016/0006-291x(79)91200-2.

DOI:10.1016/0006-291x(79)91200-2

PMID:526300

Abstract

摘要

相似文献

Tetrapeptide-amide analogues of enkephalin: the role of C-terminus in determining the character of opioid activity.脑啡肽的四肽酰胺类似物：C末端在决定阿片样物质活性特征中的作用

Biochem Biophys Res Commun. 1979 Dec 28;91(4):1239-49. doi: 10.1016/0006-291x(79)91200-2.

Correlation between circular dichroism data and biological activities of 2,5 substituted enkephalin analogues.2,5-取代脑啡肽类似物的圆二色性数据与生物活性之间的相关性

Life Sci. 1980 Jul 14;27(2):129-33. doi: 10.1016/0024-3205(80)90454-3.

Acetaldehyde-enkephalins: pronounced changes in the opiate activity of methionine-enkephalin and leucine-enkephalin on reaction with acetaldehyde.乙醛脑啡肽：甲硫氨酸脑啡肽和亮氨酸脑啡肽与乙醛反应后阿片样活性的显著变化。

FEBS Lett. 1980 Apr 21;113(1):99-101. doi: 10.1016/0014-5793(80)80504-7.

Structure-activity relationships of met5- and leu5-enkephalin analogues.

Clin Exp Pharmacol Physiol. 1979 Sep-Oct;6(5):535-40. doi: 10.1111/j.1440-1681.1979.tb00036.x.

Potent tetrapeptide enkephalins.强效四肽脑啡肽。

Life Sci. 1981 Mar 30;28(13):1517-22. doi: 10.1016/0024-3205(81)90384-2.

Super-active enkephalin analogues. Simple tripeptide hydroxyalkylamides exhibit surprisingly high and long-lasting opioid activities.超活性脑啡肽类似物。简单的三肽羟烷基酰胺表现出惊人的高且持久的阿片样活性。

Naturwissenschaften. 1981 Apr;68(4):210-2. doi: 10.1007/BF01047210.

Demonstration of the crucial role of the phenylalanine moiety in enkephalin analogues for differential recognition of the mu- and delta-receptors.

Eur J Pharmacol. 1979 Nov 23;60(1):109-10. doi: 10.1016/0014-2999(79)90059-1.

Opioid peptides derived from pre-proenkephalin B sequence: biological evaluation in guinea pig ileum and mouse vas deferens.

Proc West Pharmacol Soc. 1983;26:85-8.

Rat vas deferens: a specific bioassay for endogenous opioid peptides.大鼠输精管：一种用于内源性阿片肽的特异性生物测定法。

Br J Pharmacol. 1978 Nov;64(3):327-9. doi: 10.1111/j.1476-5381.1978.tb08653.x.

In vitro profile of some opioid pentapeptide analogues.某些阿片类五肽类似物的体外概况

Eur J Pharmacol. 1978 Jun 1;49(3):313-7. doi: 10.1016/0014-2999(78)90109-7.

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Efficient Synthesis of Norbuprenorphines Coupled with Enkephalins and Investigation of Their Permeability.诺布普啡与脑啡肽偶联物的高效合成及其渗透性研究

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Development of novel enkephalin analogues that have enhanced opioid activities at both mu and delta opioid receptors.开发在μ和δ阿片受体上均具有增强阿片活性的新型脑啡肽类似物。

J Med Chem. 2007 Nov 1;50(22):5528-32. doi: 10.1021/jm061465o. Epub 2007 Oct 10.

The effects of long-term treatment of NG108-15 cells with penta- and tetrapeptide enkephalin dimers on opioid receptor binding and cyclic AMP (cAMP) levels.用五肽和四肽脑啡肽二聚体对NG108-15细胞进行长期处理对阿片受体结合及环磷酸腺苷（cAMP）水平的影响。

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