Effect of erythro-9-(2-hydroxy-3-nonyl) adenine on purine and pyrimidine metabolism in the human peripheral lymphocyte during the early phases of phytohemagglutinin-mediated blastogenesis.
作者信息
Skupp S, Vugrek G, Ayvazian J H
出版信息
Biochem Pharmacol. 1979 Nov 15;28(22):3323-31. doi: 10.1016/0006-2952(79)90128-x.
PMID:526339
Abstract
摘要
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Effect of erythro-9-(2-hydroxy-3-nonyl) adenine on purine and pyrimidine metabolism in the human peripheral lymphocyte during the early phases of phytohemagglutinin-mediated blastogenesis.
Biochem Pharmacol. 1979 Nov 15;28(22):3323-31. doi: 10.1016/0006-2952(79)90128-x.
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Suppression of human lymphocyte DNA and protein synthesis in vitro by adenosine and eight modified adenine nucleosides in the presence or in the absence of adenosine deaminase inhibitors, 2'-deoxycoformycin (DCF) and erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA).
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Inhibition of human T-cell rosette formation by the adenosine deaminase inhibitor erythro-9-(2-hydroxy-3-nonyl) adenine hydrochloride (EHNA).
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Effects of the chiral isomers of erythro- and threo-9-(2-hydroxy-3-nonyl)adenine on purine metabolism in sarcoma 180 cells.
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Effect of chirality in erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) on adenosine deaminase inhibition.赤型-9-(2-羟基-3-壬基)腺嘌呤（EHNA）的手性对腺苷脱氨酶抑制作用的影响。
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Inhibition of methylation by adenosine in adenosine deaminase-inhibited, phytohemagglutinin-stimulated human lymphocytes.
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Adenosine deaminase inhibitors. Conversion of a single chiral synthon into erythro- and threo-9-(2-hydroxy-3-nonyl)adenines.腺苷脱氨酶抑制剂。将单一手性合成子转化为赤藓型和苏阿糖型-9-(2-羟基-3-壬基)腺嘌呤。
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Adenosine deaminase inhibitors. Synthesis of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.腺苷脱氨酶抑制剂。赤藓糖型-9-(2-羟基-3-壬基)腺嘌呤的脱氮类似物的合成。
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