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Adenosine deaminase inhibitors: their role in chemotherapy and immunosuppression.

作者信息

Glazer R I

出版信息

Cancer Chemother Pharmacol. 1980;4(4):227-35. doi: 10.1007/BF00255266.

DOI:10.1007/BF00255266
PMID:7002342
Abstract
摘要

相似文献

1
Adenosine deaminase inhibitors: their role in chemotherapy and immunosuppression.腺苷脱氨酶抑制剂：它们在化疗和免疫抑制中的作用。
Cancer Chemother Pharmacol. 1980;4(4):227-35. doi: 10.1007/BF00255266.
2
Potentiation of cytotoxicity and antitumor activity of adenosine analogs by the adenosine deaminase inhibitor adecypenol.腺苷脱氨酶抑制剂阿德西培诺增强腺苷类似物的细胞毒性和抗肿瘤活性。
J Antibiot (Tokyo). 1989 Nov;42(11):1722-4. doi: 10.7164/antibiotics.42.1722.
3
Inhibitors of adenosine deaminase.腺苷脱氨酶抑制剂
Pharmacol Ther. 1982;17(3):399-429. doi: 10.1016/0163-7258(82)90023-7.
4
Inhibitors of adenosine deaminase and the development of antiviral agents.腺苷脱氨酶抑制剂与抗病毒药物的研发
Ann N Y Acad Sci. 1985;451:204-14. doi: 10.1111/j.1749-6632.1985.tb27111.x.
5
Enhancement of the biological activity of cordycepin (3'-deoxyadenosine) by the adenosine deaminase inhibitor 2'-deoxycoformycin.腺苷脱氨酶抑制剂2'-脱氧助间型霉素增强虫草素（3'-脱氧腺苷）的生物活性
Biochem Pharmacol. 1976 Jun 15;25(12):1441-4. doi: 10.1016/0006-2952(76)90121-0.
6
Identification of the bioactive enantiomer of erythro-3-(adenin-9-yl)-2-nonanol (EHNA), a semi-tight binding inhibitor of adenosine deaminase.腺苷脱氨酶半紧密结合抑制剂赤藓糖型-3-（腺嘌呤-9-基）-2-壬醇（EHNA）生物活性对映体的鉴定
Biochem Pharmacol. 1981 May 15;30(10):1159-61. doi: 10.1016/0006-2952(81)90460-3.
7
Enhancement of the biological activity of adenosine analogs by the adenosine deaminase inhibitor 2'-deoxycoformycin.腺苷脱氨酶抑制剂2'-脱氧助间型霉素增强腺苷类似物的生物活性
Pharmacology. 1977;15(1):84-9. doi: 10.1159/000136666.
8
Effect of chirality in erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) on adenosine deaminase inhibition.赤型-9-(2-羟基-3-壬基)腺嘌呤（EHNA）的手性对腺苷脱氨酶抑制作用的影响。
Biochem Pharmacol. 1982 Mar 1;31(5):879-82. doi: 10.1016/0006-2952(82)90479-8.
9
Toxicities of adenosine and 2'-deoxyadrenosine in L cells treated with inhibitors of adenosine deaminase.用腺苷脱氨酶抑制剂处理的L细胞中腺苷和2'-脱氧腺苷的毒性。
Biochem Pharmacol. 1977 Jan 1;26(1):71-6. doi: 10.1016/0006-2952(77)90135-6.
10
Tight-binding inhibitors--IV. Inhibition of adenosine deaminases by various inhibitors.紧密结合抑制剂——IV. 各种抑制剂对腺苷脱氨酶的抑制作用
Biochem Pharmacol. 1977 Mar 1;26(5):359-67. doi: 10.1016/0006-2952(77)90192-7.

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J Biomol Struct Dyn. 2022 Jul;40(11):5112-5127. doi: 10.1080/07391102.2020.1868337. Epub 2021 Jan 5.
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A new mixed inhibitor of adenosine deaminase produced by endophytic Cochliobolus sp. from medicinal plant seeds.一种从药用植物种子内生 Cochliobolus sp. 中产生的新型腺苷脱氨酶混合抑制剂。
Folia Microbiol (Praha). 2020 Apr;65(2):293-302. doi: 10.1007/s12223-019-00723-1. Epub 2019 Jul 4.
3

本文引用的文献

1
(S)-9-(2,3-Dihydroxypropyl)adenine: An Aliphatic Nucleoside Analog with Broad-Spectrum Antiviral Activity.(S)-9-(2,3-二羟丙基)腺嘌呤：一种具有广谱抗病毒活性的脂肪族核苷类似物。
Science. 1978 May 5;200(4341):563-5. doi: 10.1126/science.200.4341.563.
2
Determination of plaque inhibitory activity of adenine arabinoside (9-beta-D-arabinofuranosyladenine) for herpesviruses using an adenosine deaminase inhibitor.使用腺苷脱氨酶抑制剂测定阿糖腺苷（9-β-D-阿拉伯呋喃糖基腺嘌呤）对疱疹病毒的噬斑抑制活性。
Antimicrob Agents Chemother. 1974 Jul;6(1):98-101. doi: 10.1128/AAC.6.1.98.
3
ENZYME INHIBITORS. V. THE SYNTHESES OF 6-SUBSTITUTED-(9-HYDROXYALKYL)PURINES AND THEIR EVALUATION AS INHIBITORS OF ADENOSINE DEAMINASE.
Fluorescing Isofunctional Ribonucleosides: Assessing Adenosine Deaminase Activity and Inhibition.
荧光同功核糖核苷：评估腺苷脱氨酶活性和抑制作用。
Chembiochem. 2019 Mar 1;20(5):718-726. doi: 10.1002/cbic.201800665. Epub 2019 Feb 21.
4
Targeting Metalloenzymes for Therapeutic Intervention.靶向金属酶治疗干预。
Chem Rev. 2019 Jan 23;119(2):1323-1455. doi: 10.1021/acs.chemrev.8b00201. Epub 2018 Sep 7.
5
Identification of a New Uncompetitive Inhibitor of Adenosine Deaminase from Endophyte Aspergillus niger sp.从内生真菌黑曲霉中鉴定出一种新型腺苷脱氨酶非竞争性抑制剂
Curr Microbiol. 2018 May;75(5):565-573. doi: 10.1007/s00284-017-1418-4. Epub 2017 Dec 14.
6
Effects of aqueous extract from Silybum marianum on adenosine deaminase activity in cancerous and noncancerous human gastric and colon tissues.水飞蓟提取物对人胃癌和结肠癌组织中癌组织与非癌组织腺苷脱氨酶活性的影响。
Pharmacogn Mag. 2015 Jan-Mar;11(41):143-6. doi: 10.4103/0973-1296.149729.
7
Aqueous extract from taxus baccata inhibits adenosine deaminase activity significantly in cancerous and noncancerous human gastric and colon tissues.欧洲红豆杉水提取物可显著抑制人胃癌和结肠癌组织（包括癌组织和非癌组织）中的腺苷脱氨酶活性。
Pharmacogn Mag. 2014 Apr;10(Suppl 2):S214-6. doi: 10.4103/0973-1296.133232.
8
Enzymatic interconversion of isomorphic fluorescent nucleosides: adenosine deaminase transforms an adenosine analogue into an inosine analogue.同构荧光核苷的酶促相互转化：腺苷脱氨酶将腺苷类似物转化为肌苷类似物。
Angew Chem Int Ed Engl. 2013 Dec 23;52(52):14026-30. doi: 10.1002/anie.201307064. Epub 2013 Nov 29.
9
A new strategy based on pharmacophore-based virtual screening in adenosine deaminase inhibitors detection and in-vitro study.基于药效团的虚拟筛选的新型策略在腺苷脱氨酶抑制剂检测和体外研究中的应用。
Daru. 2012 Oct 22;20(1):64. doi: 10.1186/2008-2231-20-64.
10
Contrasting behavior of conformationally locked carbocyclic nucleosides of adenosine and cytidine as substrates for deaminases.作为脱氨酶底物的腺苷和胞苷的构象锁定碳环核苷的对比行为。
Nucleosides Nucleotides Nucleic Acids. 2009 May;28(5):614-32. doi: 10.1080/15257770903091904.
Biochemistry. 1965 Jan;4:71-6. doi: 10.1021/bi00877a013.
4
Evidence that the inhibitory effect of adenosine, but not cordycepin, on the methylation of nuclear RNA is mediated by S-adenosylhomocysteine hydrolase.
Mol Pharmacol. 1980 Nov;18(3):483-90.
5
Metabolism and disposition of erythro-9-(2-hydroxy-3-nonyl)[14C]adenine in the rhesus monkey.恒河猴中erythro-9-(2-羟基-3-壬基)[14C]腺嘌呤的代谢与处置
Drug Metab Dispos. 1980 Jan-Feb;8(1):5-7.
6
Mode of inhibition of coformycin on adenosine deaminase.助间型霉素对腺苷脱氨酶的抑制方式。
J Antibiot (Tokyo). 1967 Jul;20(4):227-31.
7
Specificity of adenosine deaminase toward adenosine and 2'-deoxyadenosine analogues.腺苷脱氨酶对腺苷及2'-脱氧腺苷类似物的特异性
Arch Biochem Biophys. 1966 Feb;113(2):383-8. doi: 10.1016/0003-9861(66)90202-5.
8
A kinetic study of the deamination of some adenosine analogues. Substrate specificity of adenosine deaminase.某些腺苷类似物脱氨作用的动力学研究。腺苷脱氨酶的底物特异性。
Can J Biochem. 1966 Mar;44(3):331-7. doi: 10.1139/o66-039.
9
Structure of coformycin, an unusual nucleoside of microbial origin.助间型霉素的结构，一种源自微生物的特殊核苷。
J Am Chem Soc. 1974 Jun 26;96(13):4327-8. doi: 10.1021/ja00820a049.
10
Molecular form of adenosine deaminase in severe combined immunodeficiency.重症联合免疫缺陷中腺苷脱氨酶的分子形式
Biochem Biophys Res Commun. 1974 Apr 8;57(3):590-5. doi: 10.1016/0006-291x(74)90587-7.