新生哺乳动物中6-羟基多巴胺对交感神经细胞的破坏作用。
Sympathetic nerve cell destruction in newborn mammals by 6-hydroxydopamine.
作者信息
Angeletti P U, Levi-Montalcini R
出版信息
Proc Natl Acad Sci U S A. 1970 Jan;65(1):114-21. doi: 10.1073/pnas.65.1.114.
Abstract
A selective and permanent destruction of sympathetic ganglia was achieved by injecting 6-hydroxydopamine in newborn animals. A lifelong chemical sympathectomy may thus be obtained. The process of cell damage and destruction is substantially different from that produced with an antiserum to a specific nerve growth factor.
摘要
通过向新生动物注射6-羟基多巴胺，实现了对交感神经节的选择性和永久性破坏。由此可获得终身化学性交感神经切除术。细胞损伤和破坏的过程与用针对特定神经生长因子的抗血清所产生的过程有很大不同。
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