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核磁共振光谱法：一些常见核苷酸的13C光谱。

Nuclear magnetic resonance spectroscopy: 13C spectra of some common nucleotides.

作者信息

Dorman D E, Roberts J D

出版信息

Proc Natl Acad Sci U S A. 1970 Jan;65(1):19-26. doi: 10.1073/pnas.65.1.19.

DOI:10.1073/pnas.65.1.19
PMID:5263750
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC286184/
Abstract

Natural-abundance (13)C nuclear magnetic resonance spectra of ten common nucleotides in neutral, aqueous solutions have been determined and interpreted. The spectra of two of these substances were also determined in acidic solutions, and several of the carbon chemical shifts were found to depend markedly on pH. Within the limited range of concentrations employed, there were observed no carbon chemical-shift changes which could be ascribed to base-stacking or base-pairing phenomena.

摘要

已测定并解释了中性水溶液中十种常见核苷酸的天然丰度（13）C核磁共振谱。还测定了其中两种物质在酸性溶液中的谱，发现几个碳化学位移明显依赖于pH值。在所采用的有限浓度范围内，未观察到可归因于碱基堆积或碱基配对现象的碳化学位移变化。

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本文引用的文献

1
Natural-abundance C nuclear magnetic resonance spectra of medium-molecular-weight organic compounds.中等分子量有机化合物的天然丰度碳核磁共振谱
Proc Natl Acad Sci U S A. 1968 Aug;60(4):1152-5. doi: 10.1073/pnas.60.4.1152.
2
Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid.核酸的分子结构；脱氧核糖核酸的一种结构。
Nature. 1953 Apr 25;171(4356):737-8. doi: 10.1038/171737a0.
3
Nuclear magnetic resonance spectroscopy. Benzene-13C.
J Am Chem Soc. 1967 Jun 7;89(12):2967-9. doi: 10.1021/ja00988a029.
4
Proton magnetic resonance studies of ribose dinucleoside monophoshates in aqueous solution. I. The nature of the base-stacking interaction in adenylyl 3'--5')adenosine.核糖二核苷单磷酸盐水溶液的质子磁共振研究。I. 腺苷酰基（3'-5'）腺苷中碱基堆积相互作用的本质。
J Am Chem Soc. 1969 Jan 1;91(1):168-83. doi: 10.1021/ja01029a033.
5
Carbon-13 nuclear magnetic resonance: naturally occurring nucleosides.碳-13核磁共振：天然存在的核苷。
Proc Natl Acad Sci U S A. 1970 Jan;65(1):27-30. doi: 10.1073/pnas.65.1.27.