Que L, Willie G R, Cashel M, Bodley J W, Gray G R
Proc Natl Acad Sci U S A. 1973 Sep;70(9):2563-6. doi: 10.1073/pnas.70.9.2563.
Guanosine tetraphosphate, recently discovered to mediate the regulatory relationship between protein synthesis and RNA accumulation in various bacteria, has been synthesized in vitro in large quantities and analyzed by natural-abundance (13)C nuclear magnetic resonance spectroscopy in order to confirm its structure and establish the positions of phosphate attachment. These studies have established its structure as guanosine 5'-diphosphate, 3'-diphosphate.
最近发现鸟苷四磷酸可介导多种细菌中蛋白质合成与RNA积累之间的调控关系，现已在体外大量合成，并通过天然丰度的（13）C核磁共振光谱进行分析，以确认其结构并确定磷酸基团连接的位置。这些研究确定其结构为5'-二磷酸鸟苷，3'-二磷酸鸟苷。
