5'-二磷酸鸟苷-3'-二磷酸：通过碳-13核磁共振光谱法确定结构
Guanosine 5'-diphosphate, 3'-diphosphate: assignment of structure by 13C nuclear magnetic resonance spectroscopy.
作者信息
Que L, Willie G R, Cashel M, Bodley J W, Gray G R
出版信息
Proc Natl Acad Sci U S A. 1973 Sep;70(9):2563-6. doi: 10.1073/pnas.70.9.2563.
Abstract
Guanosine tetraphosphate, recently discovered to mediate the regulatory relationship between protein synthesis and RNA accumulation in various bacteria, has been synthesized in vitro in large quantities and analyzed by natural-abundance (13)C nuclear magnetic resonance spectroscopy in order to confirm its structure and establish the positions of phosphate attachment. These studies have established its structure as guanosine 5'-diphosphate, 3'-diphosphate.
摘要
最近发现鸟苷四磷酸可介导多种细菌中蛋白质合成与RNA积累之间的调控关系，现已在体外大量合成，并通过天然丰度的（13）C核磁共振光谱进行分析，以确认其结构并确定磷酸基团连接的位置。这些研究确定其结构为5'-二磷酸鸟苷，3'-二磷酸鸟苷。
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