主动运输模型的分析
Analysis of a model for active transport.
作者信息
Hill T L
出版信息
Proc Natl Acad Sci U S A. 1970 Feb;65(2):409-16. doi: 10.1073/pnas.65.2.409.
Abstract
A particular model of active transport is analyzed, at steady state, by means of a diagram method for the kinetics, and supplemented by use of a free energy diagram. It is assumed that there is cyclic adsorption of adenosine triphosphate (ATP), chemical reaction to adenosine diphosphate (ADP), and desorption of ADP, on a two-state protein (the "carrier"). ATP is the "effector" for the change in state of the protein.
摘要
通过动力学的图解法，在稳态下分析了一种特定的主动运输模型，并辅以自由能图。假设在一种双态蛋白质（“载体”）上存在三磷酸腺苷（ATP）的循环吸附、化学反应生成二磷酸腺苷（ADP）以及ADP的解吸。ATP是蛋白质状态变化的“效应物”。
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