从HeLa细胞中鉴定出一种细菌生长抑制剂：一种酮醛。
Identification of a bacterial growth inhibitors from HeLa cells: a ketoaldehyde.
作者信息
Sparkes B G, Kenny C P
出版信息
Proc Natl Acad Sci U S A. 1969 Nov;64(3):920-2. doi: 10.1073/pnas.64.3.920.
Abstract
The growth-inhibiting factor found earlier in human cell cultures appeared to be a ketoaldehyde. An infrared spectral study of 2,4-dinitrophenylhydrazine derivatives suggested that the ketoaldehyde was 4-hydroxy-2-ketobutyraldehyde. The compound, when synthesized, gave the same DNPH derivatives as the natural substance.
摘要
早前在人类细胞培养物中发现的生长抑制因子似乎是一种酮醛。对2,4-二硝基苯肼衍生物的红外光谱研究表明，该酮醛为4-羟基-2-酮基丁醛。该化合物合成后，得到了与天然物质相同的2,4-二硝基苯肼衍生物。
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