Morse A R, Hutton J D, Jacobs H S, Murray M A, James V H
Br J Obstet Gynaecol. 1979 Dec;86(12):981-3. doi: 10.1111/j.1471-0528.1979.tb11249.x.
The karyopyknotic index correlated significantly (p less than 0.001) with the plasma oestradiol but not plasma oestrone concentration in 38 postmenopausal women. This ties with previous findings that postmenopausal women with superficial dyspareunia have a more severe degree of vaginal atrophy than asymptomatic women, and that oestradiol is probably more important biologically than oestrone.
在38名绝经后女性中,核固缩指数与血浆雌二醇浓度显著相关(p小于0.001),但与血浆雌酮浓度无关。这与之前的研究结果相符,即有浅表性交困难的绝经后女性比无症状女性的阴道萎缩程度更严重,并且从生物学角度来看,雌二醇可能比雌酮更重要。