Hillman J S
Br J Ophthalmol. 1979 Dec;63(12):817-21. doi: 10.1136/bjo.63.12.817.
A retrospective study of 212 eyes with acute closed-angle glaucoma is reported. A peak incidence in the sixth decade was noted and an increased incidence in females confirmed statistically. A surprising and often marked delay occurred in the presentation of many patients for treatment, but visual outcome was not influenced by such delay. Despite good control of intraocular pressure, many of the eyes suffered visual loss from optic nerve damage, and the visual outcome was not related to the height of intraocular pressure at presentation. Damage to the visual system occurred very early in the disease, probably with the initial acute rise of intraocular pressure, and eyes appear to vary in their susceptibility to such an insult. It does not appear that earlier presentation of the patient with acute glaucoma would significantly improve the visual outcome in terms of visual acuity. The short critical time before damage occurs to the eyes suggests a role for preventive ophthalmology in the detection and surgery of eyes at risk with shallow anterior chambers and narrow angles before they develop acute closed-angle glaucoma.
本文报告了一项对212例急性闭角型青光眼患者的回顾性研究。研究发现发病高峰在60岁,且女性发病率经统计学证实有所增加。许多患者在就诊治疗时出现了令人惊讶且往往显著的延迟,但视觉预后并未受此延迟影响。尽管眼压得到了良好控制,但许多眼睛仍因视神经损伤而视力丧失,且视觉预后与就诊时的眼压高度无关。视觉系统的损伤在疾病早期就已发生,可能与眼压最初的急性升高有关,而且眼睛对这种损伤的易感性似乎各不相同。就视力而言,急性青光眼患者更早就诊似乎并不能显著改善视觉预后。眼睛发生损伤前的关键时间很短,这表明预防性眼科在检测和手术治疗有浅前房和窄房角风险、可能发展为急性闭角型青光眼的眼睛方面具有重要作用。