Lansac J
Bull Cancer. 1979;66(4):435-46.
In gynaecological practice, the problem of precancerous lesions of the cervix arises under three different circumstances : --ectropion, --dysplasia, --in a young girl when the mother has taken Stilbestrol. The literature is reviewed in these three cases : --ectropion is an anatomical state which does not absolutely require treatment. According to the majority of authors it would not appear that its destruction is useful in the prophylaxis of carcinoma of the cervix; --dysplasia, although it does not always progress to a carcinoma, would seem to be a potentially malignant state, the diagnosis of which must be made by the combination of cytology, colposcopy and biopsy. Treatment is based upon the topography of the lesion, its severity and the age of the patient : either conservative if the patient is young and wishes to have children, or surgical (conisation or hysterectomy) if she is older, does not want any more children or has an additional gynaecological problem. --in the presence of a lesion in a young girl whose mother has taken Stilboestrol, precise diagnosis must be made by biopsy with surveillance and treatment of lesions of adenosis, either by progesterone pessaries or by excision.
在妇科临床中，宫颈的癌前病变问题出现在三种不同情况下：——宫颈外翻，——发育异常，——母亲服用过己烯雌酚的年轻女孩。本文对这三种情况的文献进行了综述：——宫颈外翻是一种解剖状态，并非绝对需要治疗。根据大多数作者的观点，其破坏似乎对预防宫颈癌并无益处；——发育异常虽然并非总是会发展为癌症，但似乎是一种潜在的恶性状态，其诊断必须通过细胞学、阴道镜检查和活检相结合来进行。治疗基于病变的部位、严重程度以及患者的年龄：如果患者年轻且想要孩子，则采用保守治疗；如果患者年龄较大、不再想要孩子或有其他妇科问题，则采用手术治疗（锥形切除术或子宫切除术）。——对于母亲服用过己烯雌酚的年轻女孩出现的病变，必须通过活检进行精确诊断，并对腺病病变进行监测和治疗，可采用孕酮阴道栓剂或切除术。
