Mather H M, Nisbet J A, Burton G H, Poston G J, Bland J M, Bailey P A, Pilkington T R
Clin Chim Acta. 1979 Jul 16;95(2):235-42. doi: 10.1016/0009-8981(79)90364-4.
The plasma magnesium (Mg) concentrations of 582 unselected diabetic outpatients and 140 control subjects were measured by atomic absorption spectrophotometry. Mean plasma Mg (+/-S.D.) was significantly lower in the diabetic patients (0.737 +/- 0.071 mmol/l) than in the control subjects (0.810 +/- 0.057 mmol/l), and 146 (25%) diabetics had values below those of all control subjects except one. Plasma Mg correlated best with clinic blood glucose concentration (r = -0.32, p less than 0.001) and other significant associations were observed with glycosuria, age, sex, insulin therapy and biguanide therapy. Although its significance is unclear, hypomagnesaemia could conceivably predispose to ischaemic heart disease in diabetes.
采用原子吸收分光光度法测定了582例未经挑选的糖尿病门诊患者和140例对照者的血浆镁（Mg）浓度。糖尿病患者的平均血浆镁（±标准差）（0.737±0.071 mmol/L）显著低于对照者（0.810±0.057 mmol/L），146例（25%）糖尿病患者的值低于除1例之外的所有对照者。血浆镁与临床血糖浓度相关性最佳（r = -0.32，p<0.001），并观察到与糖尿、年龄、性别、胰岛素治疗和双胍类治疗存在其他显著关联。尽管其意义尚不清楚，但低镁血症可能会使糖尿病患者易患缺血性心脏病。
