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哺乳动物组织中的丝氨酰 - tRNA:脑和肝脏中的色谱差异以及对密码子UGA的特异性反应。

Seryl-tRNA in mammalian tissues: chromatographic differences in brain and liver and a specific response to the codon, UGA.

作者信息

Hatfield D, Portugal F H

出版信息

Proc Natl Acad Sci U S A. 1970 Nov;67(3):1200-6. doi: 10.1073/pnas.67.3.1200.

Abstract

Differences in the elution profiles of seryl-tRNAs of beef and of rabbit liver and brain were observed. A species of beef seryl-tRNA obtained by reversed phase column chromatography that responds specifically to the codon UGA was found. In addition, a species of rabbit and of chicken seryl-tRNA that recognizes UGA was found.

摘要

观察到牛肉、兔肝和兔脑的丝氨酰 - tRNA洗脱图谱存在差异。通过反相柱色谱法获得了一种对密码子UGA有特异性反应的牛肉丝氨酰 - tRNA。此外,还发现了一种识别UGA的兔和鸡的丝氨酰 - tRNA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6968/283337/b5ce0d9d9be3/pnas00101-0124-a.jpg

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