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黑腹果蝇雄性中的自发重组

Spontaneous recombination in Drosophila melanogaster males.

作者信息

Hiraizumi Y

出版信息

Proc Natl Acad Sci U S A. 1971 Feb;68(2):268-70. doi: 10.1073/pnas.68.2.268.

DOI:10.1073/pnas.68.2.268
PMID:5277066
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC388914/
Abstract

A second chromosome of Drosophila melanogaster (symbol T-007) isolated from a natural population in Harlingen, Texas, was found to undergo recombination in heterozygous males. Heterozygous males transmit this chromosome with a frequency, k, of about 0.4, considerably reduced from the expected value of 0.5. The frequency of male recombination and the k value are negatively correlated, indicating that the two phenomena are in some way related. The complementary recombinant products are recovered in equal frequency and the recombination is not restricted to the heterochromatic regions. The time of recombination is not certain, but the distribution of recombinants is more suggestive of meiotic than of premeiotic occurrence. In the natural population of these flies, the frequency of chromosomes with male recombination is 20% or more.

摘要

从得克萨斯州哈林根的一个自然种群中分离出的黑腹果蝇的第二条染色体(符号为T - 007),被发现会在杂合雄性个体中发生重组。杂合雄性个体传递这条染色体的频率k约为0.4,相较于预期的0.5值大幅降低。雄性重组频率与k值呈负相关,表明这两种现象在某种程度上相关。互补重组产物以相等的频率被回收,并且重组并不局限于异染色质区域。重组发生的时间不确定,但重组体的分布更表明其发生在减数分裂期而非减数分裂前期。在这些果蝇的自然种群中,具有雄性重组的染色体频率为20%或更高。