Von Dreele P H, Brewster A I, Scheraga H A, Ferger M F, Du Vigneaud V
Proc Natl Acad Sci U S A. 1971 May;68(5):1028-31. doi: 10.1073/pnas.68.5.1028.
The NMR spectra at 220 MHz of lysinevasopressin and its precursors were measured in dimethyl sulfoxide, and the peaks were assigned to specific protons. Information about hydrogen bonding was obtained from the temperature coefficients of the chemical shifts. With these data, and with several chemical-shift positions and coupling constants, structural information was derived for this polypeptide hormone.
在二甲基亚砜中测量了赖氨酸加压素及其前体在220兆赫的核磁共振谱,并将各峰归属于特定的质子。通过化学位移的温度系数获得了有关氢键的信息。利用这些数据以及几个化学位移位置和耦合常数,得出了这种多肽激素的结构信息。