使用针对纯化新城疫病毒糖蛋白的抗体进行毒株比较和特性鉴定。
Use of antibodies to purified Newcastle disease virus glycoproteins for strain comparisons and characterizations.
作者信息
Avery R J, Niven J
出版信息
Infect Immun. 1979 Dec;26(3):795-801. doi: 10.1128/iai.26.3.795-801.1979.
Abstract
The H/N and F1 glycoproteins responsible for hemagglutinin/neuraminidase (H/N) activity and fusion (F1) activity were purified from several Newcastle disease virus strains and used to produce antisera. These antisera can be used to clearly distinguish the virus strains by a number of techniques including radioimmunoassay, and so provide a means of classifying new virus isolates. The variations detected between strains are not related to field virulence.
摘要
从几种新城疫病毒株中纯化出具有血凝素/神经氨酸酶（H/N）活性和融合（F1）活性的H/N和F1糖蛋白，并用于制备抗血清。这些抗血清可通过包括放射免疫分析在内的多种技术来清晰区分病毒株，从而提供一种对新病毒分离株进行分类的方法。所检测到的毒株间差异与田间毒力无关。
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