再生障碍性贫血、急性髓细胞白血病与羟甲烯龙。
Aplastic anaemia, acute myeloblastic leukaemia, and oxymetholone.
作者信息
Delamore I W, Geary C G
出版信息
Br Med J. 1971 Jun 26;2(5764):743-5. doi: 10.1136/bmj.2.5764.743.
Abstract
Four patients developed acute myeloblastic leukaemia after treatment of aplastic anaemia with oxymetholone. Two had previously shown an excellent clinical response to the drug and a third some improvement. Though no definite causal relationship between therapy and the onset of leukaemia has been established, the number of cases is greater than might have been expected by chance. The association of the two diseases is discussed.
摘要
4例再生障碍性贫血患者在接受羟甲烯龙治疗后发生急性髓细胞白血病。其中2例此前对该药显示出良好的临床反应，第3例有一定改善。虽然尚未确定治疗与白血病发病之间存在明确的因果关系，但病例数多于偶然预期。对这两种疾病的关联进行了讨论。
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本文引用的文献
1
Aplastic anaemia. Review of twenty-seven cases.再生障碍性贫血。27例病例回顾。
Lancet. 1951 Mar 24;1(6656):657-9. doi: 10.1016/s0140-6736(51)92404-x.
2
EFFECT OF OXYMETHOLONE IN REFRACTORY ANEMIA.羟甲烯龙在难治性贫血中的作用
Arch Intern Med. 1964 May;113:721-9. doi: 10.1001/archinte.1964.00280110101020.
3
Idiopathic aplastic anaemia. Incidence and management.
Lancet. 1961 Jan 14;1(7168):63-5. doi: 10.1016/s0140-6736(61)92115-8.
4
Aplastic anemia: an analysis of 50 cases.
Ann Intern Med. 1958 Aug;49(2):326-62. doi: 10.7326/0003-4819-49-2-326.
5
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J Am Med Assoc. 1953 Jul 11;152(11):1018-28. doi: 10.1001/jama.1953.03690110032010.
6
An analysis of hypoplastic anaemia with special reference to the use of oxymetholone ("Adroyd") in its therapy.再生障碍性贫血的分析，特别提及羟甲烯龙（“Adroyd”）在其治疗中的应用。
Australas Ann Med. 1968 Aug;17(3):224-35. doi: 10.1111/imj.1968.17.3.224.
7
Effect of steroids on the cycling of haemopoietic stem cells.类固醇对造血干细胞循环的影响。
Nature. 1970 Dec 19;228(5277):1204. doi: 10.1038/2281204a0.
8
Preleukaemia a report of four cases.
Acta Haematol. 1968;39(1):20-8. doi: 10.1159/000208937.
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