再生障碍性贫血、急性髓细胞白血病与羟甲烯龙。
Aplastic anaemia, acute myeloblastic leukaemia, and oxymetholone.
作者信息
Delamore I W, Geary C G
出版信息
Br Med J. 1971 Jun 26;2(5764):743-5. doi: 10.1136/bmj.2.5764.743.
Abstract
Four patients developed acute myeloblastic leukaemia after treatment of aplastic anaemia with oxymetholone. Two had previously shown an excellent clinical response to the drug and a third some improvement. Though no definite causal relationship between therapy and the onset of leukaemia has been established, the number of cases is greater than might have been expected by chance. The association of the two diseases is discussed.
摘要
4例再生障碍性贫血患者在接受羟甲烯龙治疗后发生急性髓细胞白血病。其中2例此前对该药显示出良好的临床反应，第3例有一定改善。虽然尚未确定治疗与白血病发病之间存在明确的因果关系，但病例数多于偶然预期。对这两种疾病的关联进行了讨论。
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