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通过喹吖因荧光鉴定小鼠核型，并初步确定七个连锁群。

Identification of the mouse karyotype by quinacrine fluorescence, and tentative assignment of seven linkage groups.

作者信息

Miller O J, Miller D A, Kouri R E, Allderdice P W, Dev V G, Grewal M S, Hutton J J

出版信息

Proc Natl Acad Sci U S A. 1971 Jul;68(7):1530-3. doi: 10.1073/pnas.68.7.1530.

DOI:10.1073/pnas.68.7.1530
PMID:5283942
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC389233/
Abstract

A karyotype of the mitotic chromosomes of the house mouse has been prepared based upon quinacrine fluorescence patterns. All 19 pairs of autosomes and the X and Y chromosomes have been identified. Examination of the chromosomes of the following translocation stocks, T(11;?)1Ald, T(3;?)6Ca, T(2;9)138Ca, T(2;12)163H, and T(9;13)190Ca, have led to the tentative assignments of autosomal linkage groups (LG) to chromosomes as follows: LGII to chromosome number 10 (or 13), LGIII to 12 or 15, LGIX to 16, LGXI to 6, LGXII to 19 and LGXIII to 1. By definition, LGXX is on the X chromosome.

摘要

基于喹吖因荧光模式制备了家鼠有丝分裂染色体的核型。已鉴定出所有19对常染色体以及X和Y染色体。对以下易位系T(11;?)1Ald、T(3;?)6Ca、T(2;9)138Ca、T(2;12)163H和T(9;13)190Ca的染色体进行检查后，得出常染色体连锁群（LG）与染色体的初步对应关系如下：LGII对应第10号（或13号）染色体，LGIII对应12号或15号染色体，LGIX对应16号染色体，LGXI对应6号染色体，LGXII对应19号染色体，LGXIII对应1号染色体。根据定义，LGXX位于X染色体上。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec15/389233/622931a7bbbe/pnas00082-0153-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec15/389233/622931a7bbbe/pnas00082-0153-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec15/389233/622931a7bbbe/pnas00082-0153-c.jpg

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本文引用的文献

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THE KARYOTYPE OF THE MOUSE, WITH IDENTIFICATION OF A TRANSLOCATION.小鼠的核型及一种易位的鉴定
Proc Natl Acad Sci U S A. 1965 Apr;53(4):730-7. doi: 10.1073/pnas.53.4.730.
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Cytological identification of radiation-chimaeras.辐射嵌合体的细胞学鉴定。
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A photographic representation of the variability in the G-banded structure of the chromosomes in the mouse karyotype. A guide to the identification of the individual chromosomes.小鼠核型中染色体G带结构变异的照片展示。个体染色体识别指南。
Chromosoma. 1984;89(4):294-320. doi: 10.1007/BF00292478.
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Expression of T-lymphoblast-encoded HLA-DR antigens on human T-B lymphoblast hybrids.人T-B淋巴母细胞杂交体上T淋巴母细胞编码的HLA-DR抗原的表达
Immunogenetics. 1983;17(4):411-25. doi: 10.1007/BF00372459.
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Cattanach's translocation: cytological characterization by quinacrine mustard staining.卡塔纳赫易位：用喹吖因氮芥染色进行细胞学特征分析
Proc Natl Acad Sci U S A. 1971 Dec;68(12):2918-20. doi: 10.1073/pnas.68.12.2918.
10
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Proc Natl Acad Sci U S A. 1971 Nov;68(11):2699-702. doi: 10.1073/pnas.68.11.2699.
Cytogenetics. 1967;6(2):105-19. doi: 10.1159/000129933.
4
Analysis of human metaphase chromosome set by aid of DNA-binding fluorescent agents.借助DNA结合荧光剂对人类中期染色体组进行分析。
Exp Cell Res. 1970 Oct;62(2):490-2. doi: 10.1016/0014-4827(70)90586-0.
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Nature. 1971 Apr 9;230(5293):367-9. doi: 10.1038/230367a0.
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