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通过喹吖因荧光鉴定小鼠核型,并初步确定七个连锁群。

Identification of the mouse karyotype by quinacrine fluorescence, and tentative assignment of seven linkage groups.

作者信息

Miller O J, Miller D A, Kouri R E, Allderdice P W, Dev V G, Grewal M S, Hutton J J

出版信息

Proc Natl Acad Sci U S A. 1971 Jul;68(7):1530-3. doi: 10.1073/pnas.68.7.1530.

Abstract

A karyotype of the mitotic chromosomes of the house mouse has been prepared based upon quinacrine fluorescence patterns. All 19 pairs of autosomes and the X and Y chromosomes have been identified. Examination of the chromosomes of the following translocation stocks, T(11;?)1Ald, T(3;?)6Ca, T(2;9)138Ca, T(2;12)163H, and T(9;13)190Ca, have led to the tentative assignments of autosomal linkage groups (LG) to chromosomes as follows: LGII to chromosome number 10 (or 13), LGIII to 12 or 15, LGIX to 16, LGXI to 6, LGXII to 19 and LGXIII to 1. By definition, LGXX is on the X chromosome.

摘要

基于喹吖因荧光模式制备了家鼠有丝分裂染色体的核型。已鉴定出所有19对常染色体以及X和Y染色体。对以下易位系T(11;?)1Ald、T(3;?)6Ca、T(2;9)138Ca、T(2;12)163H和T(9;13)190Ca的染色体进行检查后,得出常染色体连锁群(LG)与染色体的初步对应关系如下:LGII对应第10号(或13号)染色体,LGIII对应12号或15号染色体,LGIX对应16号染色体,LGXI对应6号染色体,LGXII对应19号染色体,LGXIII对应1号染色体。根据定义,LGXX位于X染色体上。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec15/389233/622931a7bbbe/pnas00082-0153-c.jpg

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