Goodwin R F, Whittlestone P
J Hyg (Lond). 1971 Sep;69(3):391-8. doi: 10.1017/s002217240002163x.
Hysterectomy-produced, colostrum-deprived (HPCD) pigs and naturally born, enzootic-pneumonia-free (EPF) pigs were compared with respect to their susceptibility to two strains of enzootic pneumonia induced by intranasal inoculation of suspensions of ground pneumonic tissue. All but one of the HPCD pigs developed enzootic pneumonia, whereas the EPF pigs commonly failed to develop the disease; secondly, the pneumonic lesions were more extensive in the HPCD pigs.When the dose of inoculum was increased in EPF pigs, the resulting pneumonic areas were larger.In a small, in-contact experiment the disease was also more readily transmitted to HPCD pigs than to EPF pigs.
对子宫切除、初乳缺乏(HPCD)的猪和自然出生、无地方性肺炎(EPF)的猪进行了比较,观察它们经鼻接种研磨后的肺炎组织悬液诱导的两株地方性肺炎病毒的易感性。除一头HPCD猪外,所有HPCD猪均发生了地方性肺炎,而EPF猪通常未发病;其次,HPCD猪的肺部病变更广泛。当增加EPF猪的接种剂量时,所产生的肺部病变区域更大。在一项小型的接触性实验中,该病也更容易传播给HPCD猪而非EPF猪。