通过膜免疫荧光染色检测，注射CBA淋巴细胞的C3H小鼠中的抗体反应。
Antibody response in C3H mice injected with CBA lymphoid cells as detected by membrane immunofluorescent staining.
作者信息
Lilliehöök B, Blomgren H
出版信息
Scand J Immunol. 1975;4(4):321-5. doi: 10.1111/j.1365-3083.1975.tb02632.x.
Lymphocytes from CBA mice are strongly responsive to cells from the H-2-identical strain C3H in vitro (MLC), whereas C3H lymphocytes are poorly reactive against CBA cells. Immunization of CBA mice with C3H lymphocytes did not yield any detectable specific antibodies. On the other hand, C3H mice immunized with CBA cells produced specific antibodies as detected by membrane immunofluorescence. Mice of the strains AKR and DBA/2 also possess this specific membrane alloantigen. We thus conclude that it is now possible to discriminate among lymphocytes of CBA and C3H origin.
CBA 小鼠的淋巴细胞在体外对来自 H-2 相同品系 C3H 的细胞有强烈反应（混合淋巴细胞培养），而 C3H 淋巴细胞对 CBA 细胞的反应较弱。用 C3H 淋巴细胞免疫 CBA 小鼠未产生任何可检测到的特异性抗体。另一方面，用 CBA 细胞免疫的 C3H 小鼠产生了通过膜免疫荧光检测到的特异性抗体。AKR 和 DBA/2 品系的小鼠也具有这种特异性膜同种异体抗原。因此，我们得出结论，现在有可能区分来自 CBA 和 C3H 的淋巴细胞。
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