可兴奋膜传导变化的动力学模型。
Kinetic model of conduction changes across excitable membranes.
作者信息
Jain M K, Marks R H, Cordes E H
出版信息
Proc Natl Acad Sci U S A. 1970 Oct;67(2):799-806. doi: 10.1073/pnas.67.2.799.
Abstract
A kinetic model describing conduction changes across excitable membranes is proposed. It assumes that a population of discrete membrane sites is distributed among several distinct functional states determined by the voltage across the membrane. Interconversion of these states is postulated to occur by first-order reactions. It provides a satisfactory description of the central aspects of excitable membrane behavior, including current-time and current-voltage relationships, action potential, and effects of inhibitors.
摘要
提出了一个描述可兴奋膜上传导变化的动力学模型。该模型假设一群离散的膜位点分布在由膜电压决定的几种不同功能状态之间。假定这些状态之间的相互转换通过一级反应发生。它对可兴奋膜行为的核心方面提供了令人满意的描述，包括电流-时间和电流-电压关系、动作电位以及抑制剂的作用。
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Kinetic model of conduction changes across excitable membranes.可兴奋膜传导变化的动力学模型。
Proc Natl Acad Sci U S A. 1970 Oct;67(2):799-806. doi: 10.1073/pnas.67.2.799.
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ELECTRIC IMPEDANCE OF THE SQUID GIANT AXON DURING ACTIVITY.超导巨轴突在活动期间的电阻抗。
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