Gautherie M
J Radiol. 1979 Nov;60(11):685-9.
The use of microwave hyperthermia for cancer treatment is dealt with, first analyzing the present state of the art, second from a prospective viewpoint. Follow current topics are considered: a) biological data from experiments in vitro and of animals; b) fundamental therapeutic modalities: total body hyperthermia, local hyperthermia; c) technological problems: irradiation frequency, applicators, dosimetry (non-interfering probes, microwave radiometers); d) results of preliminary clinical investigations. Prospects refer to following topics: a) technological: improvement or design of systems for producing and controlling hyperthermia; b) fundamental: models, phantoms and postoperative specimens; dielectric and thermal properties on tissues; part of the vascularization; c) clinical: treatment procedures, long-term therapeutic trials (exclusive or combined hyperthermia, cancerous and healthy tissues).
本文论述了微波热疗在癌症治疗中的应用,首先分析了当前的技术现状,其次从前瞻性的角度进行了探讨。接着考虑了以下几个方面的内容:a) 体外实验和动物实验的生物学数据;b) 基本治疗方式:全身热疗、局部热疗;c) 技术问题:辐射频率、施源器、剂量测定(非干扰性探头、微波辐射计);d) 初步临床研究结果。展望涉及以下几个主题:a) 技术方面:改进或设计产生和控制热疗的系统;b) 基础方面:模型、体模和术后标本;组织的介电和热性能;血管化的作用;c) 临床方面:治疗程序、长期治疗试验(单纯热疗或联合热疗、癌组织和健康组织)。