Pouillaude J M, Dodat H, Chappuis J P, Salle B, Putet G, Monnet P
J Radiol. 1979 Dec;60(12):809-19.
Three cases of necrotizing and calcifying lesions of low urinary tract, buttock and adjacent perineum are reported. These lesions have been induced by direct syringe injection into an umbilical artery of 42% sodium bicarbonate solution at the dose of 5 to 6 ml/kg of body weight. Radiographic examinations are very important to study the urinary tract lesions. These have been surgically controlled in two cases. The follow up ranges from 10 to 21 1/2 months. On the bladder initial necrotizing lesions are followed by calcification and parietal retraction. These bladder lesions induce a more or less important ureterohydronephrosis. To these constant lesions are variably associated urethral calcifications and stenosis, distal ureter calcifications. These lesions seem to be related to the sodium bicarbonate hyperosmolality, to the injection conditions, and to the local hemodynamic features.
报告了3例下尿路、臀部及相邻会阴的坏死性和钙化性病变。这些病变是通过将42%碳酸氢钠溶液以5至6毫升/千克体重的剂量直接经注射器注入脐动脉所致。影像学检查对于研究尿路病变非常重要。其中2例病变已通过手术控制。随访时间为10至21.5个月。膀胱最初出现坏死性病变，随后发生钙化和膀胱壁回缩。这些膀胱病变或多或少会导致输尿管肾盂积水。除了这些持续存在的病变外，还可能伴有尿道钙化和狭窄、远端输尿管钙化。这些病变似乎与碳酸氢钠的高渗性、注射条件以及局部血流动力学特征有关。
