Falser N, Lederer B, Schwamberger K, Reissigl H
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1975 Sep 22;84(1):19-24. doi: 10.1007/BF00305685.
The distributions of acid alpha1-glycoprotein, alpha1-fetoprotein, beta-galactosidase and gastrin in gastric carcinoma and gastric ulcer as well as in the neighbourhood of these lesions were studied by means of immunohistochemical methods on imprint preparation. We could not find significant differences between gastric carcinoma and the nonneoplastic lesions, except for the acid alpha1-glycoprotein. The results of this first study indicate that the immunochemical and immunohistological assay of acid alpha1-glycoprotein might be of practical value in diagnosing malignant changes of gastric mucosa.
采用免疫组织化学方法，对印片标本进行研究，以观察酸性α1-糖蛋白、甲胎蛋白、β-半乳糖苷酶及胃泌素在胃癌、胃溃疡及其病变周围组织中的分布情况。除酸性α1-糖蛋白外，我们未发现胃癌与非肿瘤性病变之间存在显著差异。这项初步研究结果表明，酸性α1-糖蛋白的免疫化学及免疫组织学检测，对于诊断胃黏膜的恶性病变可能具有实际价值。
