土耳其中部和东部地区人血清中针对立克次体病原体的残留凝集素及其与心血管疾病的关系。
Residual agglutinins against rickettsial agents in human sera from central and eastern Turkey and their relation to cardiovascular diseases.
作者信息
Payzin S, Akan E
出版信息
Bull World Health Organ. 1966;35(2):111-7.
Many workers have shown that the recrudescence of rickettsial infections may cause cardiovascular diseases of all kinds. As Turkey is a region where rickettsial infections in man are endemic, the relation between such infections and cardiovascular disease has been further studied there. Sera were collected from patients with cardiovascular diseases and also from healthy people and patients with diseases not affecting the heart, who served as a control group. A considerably higher percentage of positive sera was obtained from the patients with cardiovascular diseases, particularly for R. prowazekii, R. conorii and C. burnetii. It was also found that the highest percentage of positive sera was obtained from people in the 20-40 years age-group. Antistreptolysin-O (ASO) determinations were also made and it was found that, on average, agglutinin-negative sera had the higher ASO titres.
许多研究人员已表明，立克次体感染的复发可能会引发各类心血管疾病。由于土耳其是人类立克次体感染的地方性流行区域，因此对该地区此类感染与心血管疾病之间的关系进行了进一步研究。采集了心血管疾病患者的血清，同时也采集了健康人群以及未患心脏疾病患者（作为对照组）的血清。心血管疾病患者血清的阳性率显著更高，尤其是针对普氏立克次体、康氏立克次体和贝氏柯克斯体。还发现，20至40岁年龄组人群的血清阳性率最高。同时也进行了抗链球菌溶血素O（ASO）检测，结果发现，平均而言，凝集素阴性的血清具有更高的ASO滴度。
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