Sterling C
Lymphology. 1979 Dec;12(4):253-6.
Inoculation of rats i.v. with dextran sulfate or polymethacrylic acid causes lymphocytosis. Electron microscopy of sections of cervical lymph nodes in control rats showed active passage of small lymphocytes through the high endothelial cells (HEC) of the post-capillary venules. In treated rats there was no indication of such passage: the HEC were free of small lymphocytes; and in about 25% of the venules apparently stationary lymphocytes, lacking microvilli, were found appressed to the luminal walls of the HEC.
给大鼠静脉注射硫酸葡聚糖或聚甲基丙烯酸会导致淋巴细胞增多。对照大鼠颈部淋巴结切片的电子显微镜检查显示,小淋巴细胞通过毛细血管后微静脉的高内皮细胞(HEC)进行活跃迁移。在接受治疗的大鼠中,没有这种迁移的迹象:高内皮细胞上没有小淋巴细胞;并且在大约25%的微静脉中,发现明显静止的、缺乏微绒毛的淋巴细胞紧贴在高内皮细胞的管腔壁上。